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    Ranbp10 RAN binding protein 10 [ Mus musculus (house mouse) ]

    Gene ID: 74334, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ranbp10provided by MGI
    Official Full Name
    RAN binding protein 10provided by MGI
    Primary source
    MGI:MGI:1921584
    See related
    Ensembl:ENSMUSG00000037415
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4432417N03Rik
    Expression
    Ubiquitous expression in liver E14.5 (RPKM 43.4), liver E14 (RPKM 37.7) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ranbp10 in Genome Data Viewer
    Location:
    8; 8 D3
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (106494940..106560463, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (105768308..105833831, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (108292208..108351250, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4933405L10 gene Neighboring gene enkurin domain containing 1 Neighboring gene glucose-fructose oxidoreductase domain containing 2 Neighboring gene translin-associated factor X (Tsnax) interacting protein 1 Neighboring gene centromere protein T Neighboring gene THAP domain containing 11

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables beta-tubulin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables guanyl-nucleotide exchange factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables small GTPase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within microtubule cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in microtubule cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145824.5NP_665823.3  ran-binding protein 10

      Status: VALIDATED

      Source sequence(s)
      AC152826
      Consensus CDS
      CCDS22613.1
      Related
      ENSMUSP00000159340.2, ENSMUST00000239468.2
      Conserved Domains (4) summary
      smart00667
      Location:257284
      LisH; Lissencephaly type-1-like homology motif
      smart00668
      Location:291347
      CTLH; C-terminal to LisH motif
      smart00757
      Location:507604
      CRA; CT11-RanBPM
      cd12909
      Location:77219
      SPRY_RanBP9_10; SPRY domain in Ran binding proteins 9 and 10

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      106494940..106560463 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030243813.1XP_030099673.1  ran-binding protein 10 isoform X1

      Conserved Domains (4) summary
      smart00667
      Location:150177
      LisH; Lissencephaly type-1-like homology motif
      smart00757
      Location:400497
      CRA; CT11-RanBPM
      cd12909
      Location:10112
      SPRY_RanBP9_10; SPRY domain in Ran binding proteins 9 and 10
      pfam10607
      Location:184238
      CLTH; CTLH/CRA C-terminal to LisH motif domain
    2. XM_030243815.1XP_030099675.1  ran-binding protein 10 isoform X3

      Conserved Domains (3) summary
      smart00667
      Location:2855
      LisH; Lissencephaly type-1-like homology motif
      smart00668
      Location:62118
      CTLH; C-terminal to LisH motif
      smart00757
      Location:278375
      CRA; CT11-RanBPM
    3. XM_030243814.1XP_030099674.1  ran-binding protein 10 isoform X2

      Conserved Domains (4) summary
      smart00667
      Location:125152
      LisH; Lissencephaly type-1-like homology motif
      smart00757
      Location:375472
      CRA; CT11-RanBPM
      pfam10607
      Location:159213
      CLTH; CTLH/CRA C-terminal to LisH motif domain
      cl02614
      Location:287
      SPRY; SPRY domain
    4. XM_006531426.1XP_006531489.1  ran-binding protein 10 isoform X3

      See identical proteins and their annotated locations for XP_006531489.1

      Conserved Domains (3) summary
      smart00667
      Location:2855
      LisH; Lissencephaly type-1-like homology motif
      smart00668
      Location:62118
      CTLH; C-terminal to LisH motif
      smart00757
      Location:278375
      CRA; CT11-RanBPM
    5. XM_011248526.1XP_011246828.1  ran-binding protein 10 isoform X3

      See identical proteins and their annotated locations for XP_011246828.1

      Conserved Domains (3) summary
      smart00667
      Location:2855
      LisH; Lissencephaly type-1-like homology motif
      smart00668
      Location:62118
      CTLH; C-terminal to LisH motif
      smart00757
      Location:278375
      CRA; CT11-RanBPM
    6. XM_006531428.5XP_006531491.1  ran-binding protein 10 isoform X4

      Conserved Domains (3) summary
      smart00668
      Location:3288
      CTLH; C-terminal to LisH motif
      smart00757
      Location:248345
      CRA; CT11-RanBPM
      cl26729
      Location:120
      LisH
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