Or2at1 olfactory receptor family 2 subfamily AT member 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Or2at1provided by MGI
Official Full Name: olfactory receptor family 2 subfamily AT member 1provided by MGI
Primary source: MGI:MGI:3030355
See related: Ensembl:ENSMUSG00000073997 AllianceGenome:MGI:3030355
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Olfr521; MOR101-2
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
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Genomic context

Location:: 7 E1; 7 54.15 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (99416371..99417337)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (99767164..99768130)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables olfactory receptor activity	ISA Inferred from Sequence Alignment more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	ISA Inferred from Sequence Alignment more info	PubMed
acts_upstream_of_or_within sensory perception of smell	ISA Inferred from Sequence Alignment more info	PubMed
involved_in signal transduction	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	ISA Inferred from Sequence Alignment more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: olfactory receptor 521

Names: GA_x6K02T2PBJ9-2443810-2444775; olfactory receptor MOR101-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_146356.2 → NP_666468.2 olfactory receptor 521

Status: VALIDATED

Source sequence(s)

AC115040

Consensus CDS

CCDS21487.1

UniProtKB/TrEMBL

E9Q519, Q8VF04

Related

ENSMUSP00000095863.3, ENSMUST00000098263.3

Conserved Domains (2) summary

pfam00001
Location:46 → 295

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:46 → 313

7tm_4; Olfactory receptor