Ugt2b37 UDP glucuronosyltransferase 2 family, polypeptide B37 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ugt2b37provided by MGI
Official Full Name: UDP glucuronosyltransferase 2 family, polypeptide B37provided by MGI
Primary source: MGI:MGI:2148239
See related: Ensembl:ENSMUSG00000057425 AllianceGenome:MGI:2148239
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 0610033E06Rik
Summary: Predicted to enable glucuronosyltransferase activity. Located in mitochondrial inner membrane. Is expressed in urinary system. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to human UGT2B15 (UDP glucuronosyltransferase family 2 member B15) and UGT2B17 (UDP glucuronosyltransferase family 2 member B17). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in liver adult (RPKM 4.9) and kidney adult (RPKM 0.5) See more
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Genomic context

Location:: 5 E1; 5 43.56 cM

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	5	NC_000071.7 (87388351..87402647, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	5	NC_000071.6 (87240492..87254788, complement)

Chromosome 5 - NC_000071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables glucuronosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glucuronosyltransferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cellular glucuronidation	IBA Inferred from Biological aspect of Ancestor more info
involved_in estrogen metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in steroid metabolic process	ISO Inferred from Sequence Orthology more info
involved_in xenobiotic glucuronidation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in mitochondrial inner membrane	HDA more info	PubMed
located_in nuclear outer membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: UDP glucuronosyltransferase 2 family, polypeptide B37

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_053215.3 → NP_444445.2 UDP glucuronosyltransferase 2 family, polypeptide B37 precursor

See identical proteins and their annotated locations for NP_444445.2

Status: PROVISIONAL

Source sequence(s)

AC100269

Consensus CDS

CCDS19386.1

UniProtKB/Swiss-Prot

P17717

UniProtKB/TrEMBL

Q8VCN3

Related

ENSMUSP00000075255.4, ENSMUST00000075858.4

Conserved Domains (3) summary

PHA03392
Location:270 → 489

egt; ecdysteroid UDP-glucosyltransferase; Provisional

pfam00201
Location:24 → 527

UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

cl10013
Location:42 → 174

Glycosyltransferase_GTB_type; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate ...