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    Pop7 processing of precursor 7, ribonuclease P family, (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 74097, updated on 30-Apr-2024

    Summary

    Official Symbol
    Pop7provided by MGI
    Official Full Name
    processing of precursor 7, ribonuclease P family, (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1921347
    See related
    Ensembl:ENSMUSG00000029715 AllianceGenome:MGI:1921347
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rpp20; 0610037N12Rik
    Summary
    Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in RNA phosphodiester bond hydrolysis, endonucleolytic and tRNA 5'-leader removal. Predicted to act upstream of or within rRNA processing. Predicted to be located in nucleolus. Predicted to be part of multimeric ribonuclease P complex and ribonuclease MRP complex. Predicted to be active in nucleus. Orthologous to human POP7 (POP7 homolog, ribonuclease P/MRP subunit). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in ovary adult (RPKM 22.5), large intestine adult (RPKM 22.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    Location:
    5 G2; 5 76.51 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (137499701..137500682, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (137501439..137502429, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38725 Neighboring gene predicted gene, 36056 Neighboring gene erythropoietin Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:137943213-137943434 Neighboring gene RIKEN cDNA 9130604C24 gene Neighboring gene GRB10 interacting GYF protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ribonuclease P RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to ribonuclease P activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA 5'-leader removal ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in tRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    part_of multimeric ribonuclease P complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nucleolar ribonuclease P complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of ribonuclease MRP complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ribonuclease P protein subunit p20
    Names
    Pop7 homolog
    RNaseP protein p20
    NP_083029.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028753.3NP_083029.1  ribonuclease P protein subunit p20

      See identical proteins and their annotated locations for NP_083029.1

      Status: VALIDATED

      Source sequence(s)
      AC148018
      Consensus CDS
      CCDS19768.1
      UniProtKB/Swiss-Prot
      Q9DCH2
      Related
      ENSMUSP00000031728.5, ENSMUST00000031728.5
      Conserved Domains (1) summary
      pfam12328
      Location:33133
      Rpp20; Rpp20 subunit of nuclear RNase MRP and P

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      137499701..137500682 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)