Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Mpo myeloperoxidase [ Mus musculus (house mouse) ]

    Gene ID: 17523, updated on 5-Jul-2021

    Summary

    Official Symbol
    Mpoprovided by MGI
    Official Full Name
    myeloperoxidaseprovided by MGI
    Primary source
    MGI:MGI:97137
    See related
    Ensembl:ENSMUSG00000009350
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA4033
    Expression
    Biased expression in liver E14.5 (RPKM 72.3), liver E14 (RPKM 65.9) and 2 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Mpo in Genome Data Viewer
    Location:
    11 52.22 cM; 11 C
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (87684610..87695238)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (87793784..87804412)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (87607286..87617914)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene TSPO associated protein 1 Neighboring gene Mpo distal enhancer region Neighboring gene Mpo proximal enhancer and promoter region Neighboring gene lactoperoxidase Neighboring gene MKS transition zone complex subunit 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA4033

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables heparin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peroxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables peroxidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables peroxidase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables peroxidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in azurophil granule ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in secretory granule ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010824.2NP_034954.2  myeloperoxidase precursor

      See identical proteins and their annotated locations for NP_034954.2

      Status: VALIDATED

      Source sequence(s)
      AK220229, BC053912, BY352425, CA547566, CN661559
      Consensus CDS
      CCDS25217.1
      UniProtKB/Swiss-Prot
      P11247
      UniProtKB/TrEMBL
      Q571G0, Q7TMS4
      Related
      ENSMUSP00000020779.5, ENSMUST00000020779.11
      Conserved Domains (2) summary
      cd09824
      Location:289702
      myeloperoxidase_like; Myeloperoxidases, eosinophil peroxidases, and lactoperoxidases
      pfam03098
      Location:147685
      An_peroxidase; Animal haem peroxidase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      87684610..87695238
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center