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    Spag9 sperm associated antigen 9 [ Mus musculus (house mouse) ]

    Gene ID: 70834, updated on 21-Apr-2024

    Summary

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    Official Symbol
    Spag9provided by MGI
    Official Full Name
    sperm associated antigen 9provided by MGI
    Primary source
    MGI:MGI:1918084
    See related
    Ensembl:ENSMUSG00000020859 AllianceGenome:MGI:1918084
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    JLP; Jip4; syd1; JIP-4; JSAP2; JSAP2a; Mapk8ip4; 3110018C07Rik; 4733401I23Rik; 4831406C20Rik
    Summary
    Enables several functions, including MAP-kinase scaffold activity; kinesin binding activity; and protein kinase binding activity. Acts upstream of or within several processes, including JNK cascade; positive regulation of MAPK cascade; and positive regulation of neuron differentiation. Located in perinuclear region of cytoplasm. Is expressed in central nervous system; dorsal root ganglion; retina; and trigeminal nerve. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and liver cirrhosis. Orthologous to human SPAG9 (sperm associated antigen 9). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E18 (RPKM 26.0), cerebellum adult (RPKM 26.0) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    11 D; 11 58.9 cM
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (93886794..94016919)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (93996046..94126093)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1144 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:93829571-93829796 Neighboring gene NME/NM23 nucleoside diphosphate kinase 2 Neighboring gene STARR-seq mESC enhancer starr_30446 Neighboring gene predicted gene, 35198 Neighboring gene NME/NM23 nucleoside diphosphate kinase 1 Neighboring gene STARR-seq mESC enhancer starr_30447 Neighboring gene ribosomal protein L27 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E5269 Neighboring gene STARR-seq mESC enhancer starr_30448 Neighboring gene STARR-seq mESC enhancer starr_30449 Neighboring gene predicted gene, 38951 Neighboring gene STARR-positive B cell enhancer ABC_E10706 Neighboring gene RIKEN cDNA B230206L02 gene Neighboring gene STARR-seq mESC enhancer starr_30450 Neighboring gene STARR-seq mESC enhancer starr_30451 Neighboring gene predicted gene, 35338 Neighboring gene VISTA enhancer mm1496 Neighboring gene STARR-seq mESC enhancer starr_30458 Neighboring gene STARR-positive B cell enhancer mm9_chr11:94071474-94071775 Neighboring gene STARR-positive B cell enhancer ABC_E467 Neighboring gene transducer of ErbB-2.1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Scaffold protein JLP mediates TCR-initiated CD4(+)T cell activation and CD154 expression. Yan Q, et al. Mol Immunol, 2017 Jul. PMID 28521278
    2. The scaffold protein JLP plays a key role in regulating ultraviolet B-induced apoptosis in mice. Enkhtuya R, et al. Genes Cells, 2014 Apr. PMID 24520900
    3. Ablation of the scaffold protein JLP causes reduced fertility in male mice. Iwanaga A, et al. Transgenic Res, 2008 Dec. PMID 18574703
    4. Peptidylarginine Deiminase 4 Promotes the Renal Infiltration of Neutrophils and Exacerbates the TLR7 Agonist-Induced Lupus Mice. Hanata N, et al. Front Immunol, 2020. PMID 32655553, Free PMC Article
    5. A negative feedback loop between JNK-associated leucine zipper protein and TGF-β1 regulates kidney fibrosis. Yan Q, et al. Commun Biol, 2020 Jun 5. PMID 32504044, Free PMC Article

    See all (67) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A negative feedback loop between JNK-associated leucine zipper protein and TGF-beta1 regulates kidney fibrosis.
      Title: A negative feedback loop between JNK-associated leucine zipper protein and TGF-β1 regulates kidney fibrosis.
    2. JLP-deficiency impaired T-cell proliferation.
      Title: Scaffold protein JLP mediates TCR-initiated CD4(+)T cell activation and CD154 expression.
    3. data establish JSAP1 and JLP as positive regulators of kinesin-1-dependent axonal transport, which prevents neuronal degeneration.
      Title: JSAP1/JIP3 and JLP regulate kinesin-1-dependent axonal transport to prevent neuronal degeneration.
    4. JSAP1 and JLP play critical roles in kinesin-1-dependent axonal transport
      Title: Critical role of JSAP1 and JLP in axonal transport in the cerebellar Purkinje cells of mice.
    5. JSAP1 and JLP, which might be paralogous to each other, are critical and functionally redundant in cytokinesis and control ARF6 localization to the midbody by forming a tripartite complex of JSAP1/JLP, active ARF6, and kinesin-1.
      Title: JSAP1 and JLP are required for ARF6 localization to the midbody in cytokinesis.
    6. JLP in skin basal keratinocytes plays an important role in UVB-induced apoptosis by modulating p38 MAPK signaling pathways.
      Title: The scaffold protein JLP plays a key role in regulating ultraviolet B-induced apoptosis in mice.
    7. Data indicate a role of a scaffolding protein JLP in the regulation of surface CD40 expression and fine-tuning of dendritic cell (DC) function.
      Title: A novel role of the scaffolding protein JLP in tuning CD40-induced activation of dendritic cells.
    8. A functional role for JLP in the gep oncogene-regulated neoplastic signaling pathway.
      Title: Neoplastic transformation induced by the gep oncogenes involves the scaffold protein JNK-interacting leucine zipper protein.
    9. Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furin.
      Title: Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furin.
    10. Ablation of the scaffold protein JLP causes reduced fertility in male mice.
      Title: Ablation of the scaffold protein JLP causes reduced fertility in male mice.
    Submit: New GeneRIF Correction See all GeneRIFs (14)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2)  1 citation
    • Chemically induced (ENU) (1) 
    • Endonuclease-mediated (2) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables JUN kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables JUN kinase binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables MAP-kinase scaffold activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables MAP-kinase scaffold activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables kinesin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables kinesin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables signaling receptor complex adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in lysosome localization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of dendrite extension ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of neuron differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within positive regulation of MAPK cascade IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of MAPK cascade IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in positive regulation of cell migration ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within positive regulation of neuron differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within retrograde transport, endosome to Golgi ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within striated muscle cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    located_in lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    C-Jun-amino-terminal kinase-interacting protein 4
    Names
    JNK-associated leucine-zipper protein
    JNK-interacting leucine zipper
    JNK-interacting protein 4
    JNK/SAPK-associated protein 2
    mitogen-activated protein kinase 8-interacting protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025428.2 → NP_001020599.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK014060, BC052058, BC094670, CJ123181, CK781075, CO044222
      Consensus CDS
      CCDS36282.1
      UniProtKB/TrEMBL
      E9PUD1, F8WH31
      Related
      ENSMUSP00000090452.5, ENSMUST00000092777.11
      Conserved Domains (2) summary
      pfam15898
      Location:301 → 400
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
      pfam16471
      Location:254 → 322
      JIP_LZII; JNK-interacting protein leucine zipper II

    2. NM_001025429.2 → NP_001020600.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AK014060, AK172961, BC094670, CJ123181, CO044222
      Consensus CDS
      CCDS56797.1
      UniProtKB/TrEMBL
      F8WH31
      Related
      ENSMUSP00000075115.7, ENSMUST00000075695.13
      Conserved Domains (2) summary
      pfam15898
      Location:300 → 399
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
      pfam16471
      Location:253 → 321
      JIP_LZII; JNK-interacting protein leucine zipper II

    3. NM_001025430.2 → NP_001020601.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform 4

      See identical proteins and their annotated locations for NP_001020601.1

      Status: VALIDATED

      Source sequence(s)
      AK014060, BC094670, CJ123181, CO044222
      Consensus CDS
      CCDS25249.1
      UniProtKB/TrEMBL
      A0A0R4J196, F8WH31
      Related
      ENSMUSP00000099457.4, ENSMUST00000103168.10
      Conserved Domains (2) summary
      pfam15898
      Location:296 → 395
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
      pfam16471
      Location:249 → 317
      JIP_LZII; JNK-interacting protein leucine zipper II

    4. NM_001199203.2 → NP_001186132.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AB047782, AK147431, AK161623, AL662838, CO044222
      UniProtKB/Swiss-Prot
      Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
      Conserved Domains (4) summary
      pfam07926
      Location:56 → 162
      TPR_MLP1_2; TPR/MLP1/MLP2-like protein
      pfam09744
      Location:25 → 178
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam15898
      Location:453 → 552
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
      pfam16471
      Location:406 → 474
      JIP_LZII; JNK-interacting protein leucine zipper II

    5. NM_001199204.2 → NP_001186133.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform 6

      See identical proteins and their annotated locations for NP_001186133.1

      Status: VALIDATED

      Source sequence(s)
      AK147431, AK161623, CO044222, FJ042496
      UniProtKB/Swiss-Prot
      Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
      UniProtKB/TrEMBL
      B8X349
      Conserved Domains (4) summary
      pfam07926
      Location:56 → 162
      TPR_MLP1_2; TPR/MLP1/MLP2-like protein
      pfam09744
      Location:25 → 178
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam15898
      Location:439 → 538
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
      pfam16471
      Location:392 → 460
      JIP_LZII; JNK-interacting protein leucine zipper II

    6. NM_001199205.2 → NP_001186134.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AK147431, BC060100, CJ123181, CO044222
      UniProtKB/TrEMBL
      F8WH31
      Conserved Domains (2) summary
      pfam15898
      Location:296 → 395
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
      pfam16471
      Location:249 → 317
      JIP_LZII; JNK-interacting protein leucine zipper II

    7. NM_001363157.1 → NP_001350086.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AL662838
      UniProtKB/Swiss-Prot
      Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
      Conserved Domains (3) summary
      pfam09744
      Location:25 → 178
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:396 → 464
      JIP_LZII; JNK-interacting protein leucine zipper II
      cl25732
      Location:33 → 520
      SMC_N; RecF/RecN/SMC N terminal domain

    8. NM_027569.3 → NP_081845.2  C-Jun-amino-terminal kinase-interacting protein 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AF327451, AK030165, AK172961, BB618351, BC060506, BC094670, CO044222
      Consensus CDS
      CCDS25248.1
      UniProtKB/Swiss-Prot
      Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
      Related
      ENSMUSP00000042271.8, ENSMUST00000041956.14
      Conserved Domains (4) summary
      pfam07926
      Location:56 → 162
      TPR_MLP1_2; TPR/MLP1/MLP2-like protein
      pfam09744
      Location:25 → 178
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam15898
      Location:439 → 538
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
      pfam16471
      Location:392 → 460
      JIP_LZII; JNK-interacting protein leucine zipper II

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      93886794..94016919
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006534210.5 → XP_006534273.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X1

      See identical proteins and their annotated locations for XP_006534273.1

      UniProtKB/Swiss-Prot
      Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
      Conserved Domains (4) summary
      COG0419
      Location:22 → 539
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      pfam09744
      Location:25 → 178
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:415 → 483
      JIP_LZII; JNK-interacting protein leucine zipper II
      pfam17380
      Location:458 → 651
      DUF5401; Family of unknown function (DUF5401)

    2. XM_006534214.5 → XP_006534277.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X5

      UniProtKB/Swiss-Prot
      Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
      Conserved Domains (4) summary
      COG0419
      Location:22 → 539
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      pfam09744
      Location:25 → 178
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:415 → 483
      JIP_LZII; JNK-interacting protein leucine zipper II
      pfam17380
      Location:458 → 651
      DUF5401; Family of unknown function (DUF5401)

    3. XM_006534212.5 → XP_006534275.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X3

      UniProtKB/Swiss-Prot
      Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
      Conserved Domains (4) summary
      COG0419
      Location:22 → 534
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      pfam09744
      Location:25 → 178
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:410 → 478
      JIP_LZII; JNK-interacting protein leucine zipper II
      pfam17380
      Location:453 → 646
      DUF5401; Family of unknown function (DUF5401)

    4. XM_006534211.5 → XP_006534274.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X2

      UniProtKB/Swiss-Prot
      Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
      Conserved Domains (4) summary
      COG0419
      Location:22 → 535
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      pfam09744
      Location:25 → 178
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:411 → 479
      JIP_LZII; JNK-interacting protein leucine zipper II
      pfam17380
      Location:454 → 647
      DUF5401; Family of unknown function (DUF5401)

    5. XM_006534213.5 → XP_006534276.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X4

      UniProtKB/Swiss-Prot
      Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
      Conserved Domains (4) summary
      COG0419
      Location:22 → 530
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      pfam09744
      Location:25 → 178
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:406 → 474
      JIP_LZII; JNK-interacting protein leucine zipper II
      pfam17380
      Location:449 → 642
      DUF5401; Family of unknown function (DUF5401)

    6. XM_006534215.5 → XP_006534278.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X6

      UniProtKB/Swiss-Prot
      Q3UH77, Q3UHF0, Q58A65, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2
      Conserved Domains (4) summary
      COG0419
      Location:22 → 525
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      pfam09744
      Location:25 → 178
      Jnk-SapK_ap_N; JNK_SAPK-associated protein-1
      pfam16471
      Location:401 → 469
      JIP_LZII; JNK-interacting protein leucine zipper II
      pfam17380
      Location:444 → 637
      DUF5401; Family of unknown function (DUF5401)

    7. XM_030246314.2 → XP_030102174.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X11

      UniProtKB/TrEMBL
      F8WH31
      Conserved Domains (2) summary
      COG1196
      Location:252 → 398
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam16471
      Location:250 → 318
      JIP_LZII; JNK-interacting protein leucine zipper II

    8. XM_030246315.2 → XP_030102175.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X12

      UniProtKB/TrEMBL
      F8WH31
      Conserved Domains (3) summary
      COG1196
      Location:238 → 384
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR04523
      Location:129 → 316
      Mplasa_alph_rch; helix-rich Mycoplasma protein
      pfam16471
      Location:236 → 304
      JIP_LZII; JNK-interacting protein leucine zipper II

    9. XM_030246317.2 → XP_030102177.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X13

      UniProtKB/TrEMBL
      F8WH31
      Conserved Domains (3) summary
      COG1196
      Location:229 → 375
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR04523
      Location:129 → 307
      Mplasa_alph_rch; helix-rich Mycoplasma protein
      pfam16471
      Location:227 → 295
      JIP_LZII; JNK-interacting protein leucine zipper II

    10. XM_030246318.2 → XP_030102178.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X14

      UniProtKB/TrEMBL
      F8WH31
      Conserved Domains (3) summary
      COG1196
      Location:229 → 375
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR04523
      Location:129 → 307
      Mplasa_alph_rch; helix-rich Mycoplasma protein
      pfam16471
      Location:227 → 295
      JIP_LZII; JNK-interacting protein leucine zipper II

    11. XM_006534216.5 → XP_006534279.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X7

      UniProtKB/TrEMBL
      F8WH31
      Conserved Domains (3) summary
      COG1196
      Location:274 → 420
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR04523
      Location:165 → 352
      Mplasa_alph_rch; helix-rich Mycoplasma protein
      pfam16471
      Location:272 → 340
      JIP_LZII; JNK-interacting protein leucine zipper II

    12. XM_030246313.2 → XP_030102173.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X8

      UniProtKB/TrEMBL
      F8WH31
      Conserved Domains (3) summary
      COG1196
      Location:265 → 411
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR04523
      Location:165 → 343
      Mplasa_alph_rch; helix-rich Mycoplasma protein
      pfam16471
      Location:263 → 331
      JIP_LZII; JNK-interacting protein leucine zipper II

    13. XM_006534217.5 → XP_006534280.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X9

      UniProtKB/TrEMBL
      F8WH31
      Conserved Domains (3) summary
      COG1196
      Location:260 → 406
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR04523
      Location:151 → 338
      Mplasa_alph_rch; helix-rich Mycoplasma protein
      pfam16471
      Location:258 → 326
      JIP_LZII; JNK-interacting protein leucine zipper II

    14. XM_006534218.5 → XP_006534281.1  C-Jun-amino-terminal kinase-interacting protein 4 isoform X10

      UniProtKB/TrEMBL
      F8WH31
      Conserved Domains (2) summary
      COG1196
      Location:220 → 401
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam16471
      Location:253 → 321
      JIP_LZII; JNK-interacting protein leucine zipper II
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q58A65.2 GenPept UniProtKB/Swiss-Prot:Q58A65

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