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    Or4c3d olfactory receptor family 4 subfamily C member 3D [ Mus musculus (house mouse) ]

    Gene ID: 57272, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Or4c3dprovided by MGI
    Official Full Name
    olfactory receptor family 4 subfamily C member 3Dprovided by MGI
    Primary source
    MGI:MGI:2177523
    See related
    Ensembl:ENSMUSG00000075068 AllianceGenome:MGI:2177523
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A16; Ora16; Olfr140; MOR235-1
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
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    Genomic context

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    See Or4c3d in Genome Data Viewer
    Location:
    2 E1; 2 50.14 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (89881758..89882666, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (90051414..90052322, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily C member 3 Neighboring gene olfactory receptor family 4 subfamily X member 11 Neighboring gene THAP domain containing, apoptosis associated protein 2 pseudogene Neighboring gene olfactory receptor 1266, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Olfactory neurons expressing closely linked and homologous odorant receptor genes tend to project their axons to neighboring glomeruli on the olfactory bulb. Tsuboi A, et al. J Neurosci, 1999 Oct 1. PMID 10493742, Free PMC Article
    2. Differential development of odorant receptor expression patterns in the olfactory epithelium: a quantitative analysis in the mouse septal organ. Tian H, et al. Dev Neurobiol, 2008 Mar. PMID 18214836, Free PMC Article
    3. Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Ressler KJ, et al. Cell, 1994 Dec 30. PMID 7528109
    4. The Lim homeobox gene Lhx2 is required for olfactory sensory neuron identity. Kolterud A, et al. Development, 2004 Nov. PMID 15456728
    5. The Stimulus-Dependent Gradient of Cyp26B1+ Olfactory Sensory Neurons Is Necessary for the Functional Integrity of the Olfactory Sensory Map. Login H, et al. J Neurosci, 2015 Oct 7. PMID 26446231, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within response to stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor 4C3D
    Names
    GA_x6K02T2Q125-51484508-51483600
    odorant receptor A16
    olfactory receptor 140
    olfactory receptor 235-1
    olfactory receptor 4A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_020515.1 → NP_065261.1  olfactory receptor 4C3D

      See identical proteins and their annotated locations for NP_065261.1

      Status: PROVISIONAL

      Source sequence(s)
      AB030896
      Consensus CDS
      CCDS16405.1
      UniProtKB/Swiss-Prot
      Q60878, Q9R0K1
      UniProtKB/TrEMBL
      Q2NL40
      Related
      ENSMUSP00000097346.2, ENSMUST00000099757.2
      Conserved Domains (2) summary
      pfam00001
      Location:39 → 285
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:39 → 299
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      89881758..89882666 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q60878.2 GenPept UniProtKB/Swiss-Prot:Q60878

    Gene LinkOut

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