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    Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 [ Mus musculus (house mouse) ]

    Gene ID: 74032, updated on 23-Jun-2021

    Summary

    Official Symbol
    Sdr42e1provided by MGI
    Official Full Name
    short chain dehydrogenase/reductase family 42E, member 1provided by MGI
    Primary source
    MGI:MGI:1921282
    See related
    Ensembl:ENSMUSG00000034308
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI117603; 4632417N05Rik
    Expression
    Biased expression in liver adult (RPKM 39.3), bladder adult (RPKM 18.5) and 12 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Sdr42e1 in Genome Data Viewer
    Location:
    8; 8 E1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (118388138..118400428, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (117661399..117673689, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (120185299..120195415, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene c-Maf inducing protein Neighboring gene microRNA 7078 Neighboring gene phospholipase C, gamma 2 Neighboring gene predicted gene, 31717 Neighboring gene predicted gene, 38416

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 3-beta-hydroxy-delta5-steroid dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in steroid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    short-chain dehydrogenase/reductase family 42E member 1
    NP_001344201.1
    NP_001344202.1
    NP_083001.1
    XP_006531472.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357272.1NP_001344201.1  short-chain dehydrogenase/reductase family 42E member 1

      Status: VALIDATED

      Source sequence(s)
      AC112964, AK014586, CX243765
      Consensus CDS
      CCDS22701.1
      Conserved Domains (1) summary
      cl21454
      Location:10351
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    2. NM_001357273.1NP_001344202.1  short-chain dehydrogenase/reductase family 42E member 1

      Status: VALIDATED

      Source sequence(s)
      AC112964
      Consensus CDS
      CCDS22701.1
      Related
      ENSMUSP00000133782.2, ENSMUST00000173522.8
      Conserved Domains (1) summary
      cl21454
      Location:10351
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    3. NM_028725.4NP_083001.1  short-chain dehydrogenase/reductase family 42E member 1

      See identical proteins and their annotated locations for NP_083001.1

      Status: VALIDATED

      Source sequence(s)
      AC112964
      Consensus CDS
      CCDS22701.1
      UniProtKB/Swiss-Prot
      Q9D665
      Related
      ENSMUSP00000044457.8, ENSMUST00000037955.14
      Conserved Domains (1) summary
      cl21454
      Location:10351
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      118388138..118400428 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531409.3XP_006531472.1  short-chain dehydrogenase/reductase family 42E member 1 isoform X1

      See identical proteins and their annotated locations for XP_006531472.1

      UniProtKB/Swiss-Prot
      Q9D665
      Conserved Domains (1) summary
      cl21454
      Location:10351
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
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