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    Aldh8a1 aldehyde dehydrogenase 8 family, member A1 [ Mus musculus (house mouse) ]

    Gene ID: 237320, updated on 23-Jun-2021

    Summary

    Official Symbol
    Aldh8a1provided by MGI
    Official Full Name
    aldehyde dehydrogenase 8 family, member A1provided by MGI
    Primary source
    MGI:MGI:2653900
    See related
    Ensembl:ENSMUSG00000037542
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RAL; Raldh4
    Expression
    Biased expression in liver adult (RPKM 83.6), kidney adult (RPKM 72.6) and 3 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Aldh8a1 in Genome Data Viewer
    Location:
    10; 10 A3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (21253199..21272477)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (21377300..21396578)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (21097106..21116384)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930455C13 gene Neighboring gene Hbs1-like (S. cerevisiae) Neighboring gene predicted gene, 33803 Neighboring gene FK506 binding protein 1a, pseudogene 2 Neighboring gene predicted gene, 33945 Neighboring gene predicted gene, 33892

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables aminomuconate-semialdehyde dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
     
    enables retinal dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables retinal dehydrogenase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables retinal dehydrogenase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    2-aminomuconic semialdehyde dehydrogenase
    Names
    aldehyde dehydrogenase family 8 member A1
    retinal dehydrogenase 4
    retinal dehydrogenase type 4
    NP_848828.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178713.4NP_848828.1  2-aminomuconic semialdehyde dehydrogenase

      See identical proteins and their annotated locations for NP_848828.1

      Status: VALIDATED

      Source sequence(s)
      AC153557, AK050298
      Consensus CDS
      CCDS23723.1
      UniProtKB/Swiss-Prot
      Q8BH00
      Related
      ENSMUSP00000038878.8, ENSMUST00000042699.14
      Conserved Domains (1) summary
      cd07093
      Location:27485
      ALDH_F8_HMSADH; Human aldehyde dehydrogenase family 8 member A1-like

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      21253199..21272477
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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