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    Map4 microtubule-associated protein 4 [ Mus musculus (house mouse) ]

    Gene ID: 17758, updated on 8-Mar-2024

    Summary

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    Official Symbol
    Map4provided by MGI
    Official Full Name
    microtubule-associated protein 4provided by MGI
    Primary source
    MGI:MGI:97178
    See related
    Ensembl:ENSMUSG00000032479 AllianceGenome:MGI:97178
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MAP-4; Mtap4; Mtap-4
    Summary
    Enables microtubule binding activity. Involved in microtubule cytoskeleton organization. Acts upstream of or within establishment of spindle orientation; microtubule sliding; and mitotic spindle organization. Located in postsynaptic density. Is expressed in several structures, including central nervous system; genitourinary system; gut; musculature; and trunk mesenchyme. Orthologous to human MAP4 (microtubule associated protein 4). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 29.3), frontal lobe adult (RPKM 18.1) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Map4 in Genome Data Viewer
    Location:
    9 F2; 9 59.83 cM
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (109758909..109913018)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (109929841..110083954)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene cell division cycle 25A Neighboring gene microRNA 7089 Neighboring gene STARR-seq mESC enhancer starr_25247 Neighboring gene STARR-seq mESC enhancer starr_25250 Neighboring gene STARR-positive B cell enhancer ABC_E9336 Neighboring gene predicted gene 4644 Neighboring gene 60S ribosomal protein L7 pseudogene Neighboring gene STARR-seq mESC enhancer starr_25252 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:109964958-109965201 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:109965464-109965647 Neighboring gene STARR-seq mESC enhancer starr_25254 Neighboring gene DExH-box helicase 30 Neighboring gene STARR-positive B cell enhancer ABC_E6806 Neighboring gene predicted gene 10615 Neighboring gene predicted gene, 23377

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. miR-103-3p Regulates the Differentiation and Autophagy of Myoblasts by Targeting MAP4. Zhang X, et al. Int J Mol Sci, 2023 Feb 18. PMID 36835542, Free PMC Article
    2. Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy. Li L, et al. Cell Commun Signal, 2022 Jul 28. PMID 35902952, Free PMC Article
    3. Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice. Li L, et al. EBioMedicine, 2018 Nov. PMID 30327268, Free PMC Article
    4. A novel isoform of MAP4 organises the paraxial microtubule array required for muscle cell differentiation. Mogessie B, et al. Elife, 2015 Apr 21. PMID 25898002, Free PMC Article
    5. Basis for MAP4 dephosphorylation-related microtubule network densification in pressure overload cardiac hypertrophy. Cheng G, et al. J Biol Chem, 2010 Dec 3. PMID 20889984, Free PMC Article

    See all (61) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. miR-103-3p Regulates the Differentiation and Autophagy of Myoblasts by Targeting MAP4.
      Title: miR-103-3p Regulates the Differentiation and Autophagy of Myoblasts by Targeting MAP4.
    2. Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy.
      Title: Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy.
    3. data reveal for the first time that MAP4 drives pathological cardiac remodeling through its phosphorylation. These findings bear the therapeutic potential to ameliorate pathological cardiac remodeling by attenuating MAP4 phosphorylation.
      Title: Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice.
    4. A novel isoform of MAP4 organizes the paraxial microtubule array required for muscle cell differentiation.
      Title: A novel isoform of MAP4 organises the paraxial microtubule array required for muscle cell differentiation.
    5. This study suggested that The results suggest that MAP4 play roles in some neuron-specific events, such as the dynamic cytoskeletal reorganization and regulation of the microtubule-dependent long-range transport.
      Title: Distinct neuronal localization of microtubule-associated protein 4 in the mammalian brain.
    6. Basis for MAP4 dephosphorylation-related microtubule network densification in pressure overload cardiac hypertrophy.
      Title: Basis for MAP4 dephosphorylation-related microtubule network densification in pressure overload cardiac hypertrophy.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables microtubule stabilizing activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables tubulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell division ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    involved_in cilium disassembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within establishment of spindle orientation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within establishment of spindle orientation ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule cytoskeleton organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in microtubule cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in microtubule polymerization ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within microtubule sliding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within microtubule sliding ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    acts_upstream_of_or_within mitotic spindle organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within mitotic spindle organization ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    involved_in negative regulation of non-motile cilium assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in neuron projection development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in axon ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in axoneme ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in microtubule ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in microtubule organizing center ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in mitotic spindle ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in postsynaptic density IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    microtubule-associated protein 4
    Names
    MAP 4

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205330.2 → NP_001192259.1  microtubule-associated protein 4 isoform 1

      See identical proteins and their annotated locations for NP_001192259.1

      Status: VALIDATED

      Source sequence(s)
      AC161246
      Consensus CDS
      CCDS57704.1
      UniProtKB/Swiss-Prot
      P27546, Q05BJ2, Q3UIS2, Q3UUH5, Q3UY36, Q7TPC6, Q7TPD4, Q80YQ5, Q8CFP5
      Related
      ENSMUSP00000035055.11, ENSMUST00000035055.15
      Conserved Domains (1) summary
      pfam00418
      Location:965 → 994
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    2. NM_001205331.2 → NP_001192260.1  microtubule-associated protein 4 isoform 3

      See identical proteins and their annotated locations for NP_001192260.1

      Status: VALIDATED

      Source sequence(s)
      AC161246
      Consensus CDS
      CCDS57703.1
      UniProtKB/TrEMBL
      Q78TF3
      Related
      ENSMUSP00000131660.3, ENSMUST00000169851.8

    3. NM_001205332.2 → NP_001192261.1  microtubule-associated protein 4 isoform 4

      See identical proteins and their annotated locations for NP_001192261.1

      Status: VALIDATED

      Source sequence(s)
      AC161246
      UniProtKB/Swiss-Prot
      P27546
      Conserved Domains (1) summary
      pfam00418
      Location:927 → 956
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    4. NM_001311163.2 → NP_001298092.1  microtubule-associated protein 4 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC161246
      Consensus CDS
      CCDS81082.1
      UniProtKB/TrEMBL
      E9PZ43
      Related
      ENSMUSP00000131285.4, ENSMUST00000164930.8
      Conserved Domains (1) summary
      pfam00418
      Location:774 → 803
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    5. NM_001311164.2 → NP_001298093.1  microtubule-associated protein 4 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC161246
      Consensus CDS
      CCDS81083.1
      UniProtKB/TrEMBL
      A0A0G2JDN7
      Related
      ENSMUSP00000142439.2, ENSMUST00000199498.5
      Conserved Domains (1) summary
      pfam00418
      Location:774 → 803
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    6. NM_001419642.1 → NP_001406571.1  microtubule-associated protein 4 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC161246

    7. NM_001420115.1 → NP_001407044.1  microtubule-associated protein 4 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC161246

    8. NM_001420116.1 → NP_001407045.1  microtubule-associated protein 4 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC161246

    9. NM_001420117.1 → NP_001407046.1  microtubule-associated protein 4 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC161246

    10. NM_001420118.1 → NP_001407047.1  microtubule-associated protein 4 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC161246

    11. NM_001420119.1 → NP_001407048.1  microtubule-associated protein 4 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC161246

    12. NM_001428284.1 → NP_001415213.1  microtubule-associated protein 4 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AC161246

    13. NM_001428285.1 → NP_001415214.1  microtubule-associated protein 4 isoform 14

      Status: VALIDATED

      Source sequence(s)
      AC161246

    14. NM_001428286.1 → NP_001415215.1  microtubule-associated protein 4 isoform 15

      Status: VALIDATED

      Source sequence(s)
      AC161246

    15. NM_001428287.1 → NP_001415216.1  microtubule-associated protein 4 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC161246

    16. NM_001428288.1 → NP_001415217.1  microtubule-associated protein 4 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC161246

    17. NM_001428289.1 → NP_001415218.1  microtubule-associated protein 4 isoform 18

      Status: VALIDATED

      Source sequence(s)
      AC161246

    18. NM_001428290.1 → NP_001415219.1  microtubule-associated protein 4 isoform 19

      Status: VALIDATED

      Source sequence(s)
      AC161246

    19. NM_001428291.1 → NP_001415220.1  microtubule-associated protein 4 isoform 20

      Status: VALIDATED

      Source sequence(s)
      AC161246

    20. NM_001428292.1 → NP_001415221.1  microtubule-associated protein 4 isoform 21

      Status: VALIDATED

      Source sequence(s)
      AC161246

    21. NM_001428293.1 → NP_001415222.1  microtubule-associated protein 4 isoform 22

      Status: VALIDATED

      Source sequence(s)
      AC161246

    22. NM_001428294.1 → NP_001415223.1  microtubule-associated protein 4 isoform 23

      Status: VALIDATED

      Source sequence(s)
      AC161246

    23. NM_001428296.1 → NP_001415225.1  microtubule-associated protein 4 isoform 24

      Status: VALIDATED

      Source sequence(s)
      AC161246

    24. NM_001428297.1 → NP_001415226.1  microtubule-associated protein 4 isoform 25

      Status: VALIDATED

      Source sequence(s)
      AC161246

    25. NM_001428298.1 → NP_001415227.1  microtubule-associated protein 4 isoform 26

      Status: VALIDATED

      Source sequence(s)
      AC161246

    26. NM_001428299.1 → NP_001415228.1  microtubule-associated protein 4 isoform 27

      Status: VALIDATED

      Source sequence(s)
      AC161246

    27. NM_008633.5 → NP_032659.2  microtubule-associated protein 4 isoform 2

      See identical proteins and their annotated locations for NP_032659.2

      Status: VALIDATED

      Source sequence(s)
      AC161246
      UniProtKB/Swiss-Prot
      P27546
      Conserved Domains (1) summary
      pfam00418
      Location:965 → 994
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      109758909..109913018
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030244102.1 → XP_030099962.1  microtubule-associated protein 4 isoform X9

      Conserved Domains (3) summary
      PHA03247
      Location:532 → 828
      PHA03247; large tegument protein UL36; Provisional
      pfam05109
      Location:687 → 1042
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam00418
      Location:891 → 920
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    2. XM_036154656.1 → XP_036010549.1  microtubule-associated protein 4 isoform X14

      Conserved Domains (2) summary
      pfam05109
      Location:596 → 1004
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam00418
      Location:853 → 883
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    3. XM_036154660.1 → XP_036010553.1  microtubule-associated protein 4 isoform X18

      Conserved Domains (2) summary
      PHA03307
      Location:545 → 849
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00418
      Location:853 → 883
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    4. XM_036154661.1 → XP_036010554.1  microtubule-associated protein 4 isoform X19

      Conserved Domains (2) summary
      PHA03307
      Location:545 → 849
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00418
      Location:853 → 883
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    5. XM_036154662.1 → XP_036010555.1  microtubule-associated protein 4 isoform X20

      Conserved Domains (2) summary
      PHA03307
      Location:545 → 849
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00418
      Location:853 → 883
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    6. XM_036154663.1 → XP_036010556.1  microtubule-associated protein 4 isoform X25

      Conserved Domains (2) summary
      PHA03307
      Location:545 → 849
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00418
      Location:853 → 883
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    7. XM_036154657.1 → XP_036010550.1  microtubule-associated protein 4 isoform X15

      Conserved Domains (2) summary
      PHA03307
      Location:545 → 849
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00418
      Location:853 → 883
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    8. XM_036154658.1 → XP_036010551.1  microtubule-associated protein 4 isoform X16

      Conserved Domains (2) summary
      PHA03307
      Location:545 → 849
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00418
      Location:853 → 883
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    9. XM_036154659.1 → XP_036010552.1  microtubule-associated protein 4 isoform X17

      Conserved Domains (2) summary
      PHA03307
      Location:545 → 849
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam00418
      Location:853 → 883
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    10. XM_036154649.1 → XP_036010542.1  microtubule-associated protein 4 isoform X6

      Conserved Domains (2) summary
      PHA03247
      Location:593 → 903
      PHA03247; large tegument protein UL36; Provisional
      pfam00418
      Location:927 → 957
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    11. XM_036154648.1 → XP_036010541.1  microtubule-associated protein 4 isoform X5

      Conserved Domains (2) summary
      PHA03247
      Location:593 → 903
      PHA03247; large tegument protein UL36; Provisional
      pfam00418
      Location:927 → 957
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    12. XM_036154647.1 → XP_036010540.1  microtubule-associated protein 4 isoform X4

      Conserved Domains (2) summary
      PHA03247
      Location:593 → 903
      PHA03247; large tegument protein UL36; Provisional
      pfam00418
      Location:965 → 995
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    13. XM_036154655.1 → XP_036010548.1  microtubule-associated protein 4 isoform X13

      Conserved Domains (2) summary
      PHA03247
      Location:593 → 903
      PHA03247; large tegument protein UL36; Provisional
      pfam00418
      Location:927 → 957
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    14. XM_036154646.1 → XP_036010539.1  microtubule-associated protein 4 isoform X3

      Conserved Domains (2) summary
      PHA03247
      Location:593 → 903
      PHA03247; large tegument protein UL36; Provisional
      pfam00418
      Location:965 → 995
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    15. XM_036154654.1 → XP_036010547.1  microtubule-associated protein 4 isoform X12

      Conserved Domains (2) summary
      PHA03247
      Location:593 → 903
      PHA03247; large tegument protein UL36; Provisional
      pfam00418
      Location:927 → 957
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    16. XM_006511960.4 → XP_006512023.1  microtubule-associated protein 4 isoform X21

      Conserved Domains (2) summary
      PHA03247
      Location:516 → 750
      PHA03247; large tegument protein UL36; Provisional
      pfam00418
      Location:812 → 841
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    17. XM_017313175.3 → XP_017168664.1  microtubule-associated protein 4 isoform X23

      Conserved Domains (2) summary
      PHA03247
      Location:516 → 750
      PHA03247; large tegument protein UL36; Provisional
      pfam00418
      Location:812 → 841
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    18. XM_017313176.3 → XP_017168665.1  microtubule-associated protein 4 isoform X24

      Conserved Domains (2) summary
      PHA03247
      Location:516 → 750
      PHA03247; large tegument protein UL36; Provisional
      pfam00418
      Location:812 → 841
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    19. XM_036154664.1 → XP_036010557.1  microtubule-associated protein 4 isoform X26

      Conserved Domains (2) summary
      PHA03247
      Location:516 → 750
      PHA03247; large tegument protein UL36; Provisional
      pfam00418
      Location:812 → 842
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    20. XM_036154665.1 → XP_036010558.1  microtubule-associated protein 4 isoform X27

      Conserved Domains (2) summary
      PHA03247
      Location:516 → 750
      PHA03247; large tegument protein UL36; Provisional
      pfam00418
      Location:774 → 804
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    21. XM_017313178.3 → XP_017168667.1  microtubule-associated protein 4 isoform X29

      Conserved Domains (2) summary
      PHA03247
      Location:516 → 750
      PHA03247; large tegument protein UL36; Provisional
      pfam00418
      Location:774 → 803
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    22. XM_036154667.1 → XP_036010560.1  microtubule-associated protein 4 isoform X30

      Conserved Domains (2) summary
      PHA03247
      Location:516 → 750
      PHA03247; large tegument protein UL36; Provisional
      pfam00418
      Location:774 → 804
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    23. XM_006511962.5 → XP_006512025.1  microtubule-associated protein 4 isoform X31

      Conserved Domains (2) summary
      PHA03247
      Location:516 → 750
      PHA03247; large tegument protein UL36; Provisional
      pfam00418
      Location:774 → 803
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    24. XM_006511964.4 → XP_006512027.1  microtubule-associated protein 4 isoform X32

      Conserved Domains (2) summary
      pfam05109
      Location:528 → 889
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam00418
      Location:738 → 767
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    25. XM_017313179.2 → XP_017168668.1  microtubule-associated protein 4 isoform X34

      Conserved Domains (2) summary
      pfam05109
      Location:528 → 888
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam00418
      Location:738 → 767
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    26. XM_017313180.2 → XP_017168669.1  microtubule-associated protein 4 isoform X35

      Conserved Domains (2) summary
      pfam05109
      Location:528 → 871
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam00418
      Location:738 → 767
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    27. XM_017313181.2 → XP_017168670.1  microtubule-associated protein 4 isoform X36

      Conserved Domains (2) summary
      pfam05109
      Location:499 → 851
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam00418
      Location:700 → 729
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    28. XM_017313183.2 → XP_017168672.1  microtubule-associated protein 4 isoform X38

      Conserved Domains (2) summary
      pfam05109
      Location:499 → 851
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam00418
      Location:700 → 729
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    29. XM_017313185.3 → XP_017168674.1  microtubule-associated protein 4 isoform X40

      Conserved Domains (2) summary
      pfam00418
      Location:700 → 729
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam17823
      Location:532 → 687
      DUF5585; Family of unknown function (DUF5585)

    30. XM_017313184.2 → XP_017168673.1  microtubule-associated protein 4 isoform X39

      Conserved Domains (2) summary
      pfam05109
      Location:499 → 850
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam00418
      Location:700 → 729
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    31. XM_017313186.2 → XP_017168675.1  microtubule-associated protein 4 isoform X41

      Conserved Domains (2) summary
      pfam00418
      Location:700 → 729
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam17823
      Location:532 → 687
      DUF5585; Family of unknown function (DUF5585)

    32. XM_036154669.1 → XP_036010562.1  microtubule-associated protein 4 isoform X42

      Conserved Domains (2) summary
      pfam05109
      Location:499 → 820
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam00418
      Location:700 → 730
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    33. XM_017313187.2 → XP_017168676.1  microtubule-associated protein 4 isoform X43

      Conserved Domains (2) summary
      pfam05109
      Location:499 → 819
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam00418
      Location:700 → 729
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    34. XM_017313188.2 → XP_017168677.1  microtubule-associated protein 4 isoform X44

      Conserved Domains (2) summary
      pfam05109
      Location:499 → 819
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam00418
      Location:700 → 729
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    35. XM_017313174.3 → XP_017168663.1  microtubule-associated protein 4 isoform X22

      Conserved Domains (2) summary
      PHA03247
      Location:516 → 750
      PHA03247; large tegument protein UL36; Provisional
      pfam00418
      Location:812 → 841
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    36. XM_036154668.1 → XP_036010561.1  microtubule-associated protein 4 isoform X33

      Conserved Domains (2) summary
      pfam05109
      Location:528 → 888
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam00418
      Location:738 → 768
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    37. XM_017313182.3 → XP_017168671.1  microtubule-associated protein 4 isoform X37

      Conserved Domains (2) summary
      pfam05109
      Location:499 → 850
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam00418
      Location:700 → 729
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    38. XM_017313177.3 → XP_017168666.1  microtubule-associated protein 4 isoform X28

      Conserved Domains (2) summary
      PHA03247
      Location:516 → 750
      PHA03247; large tegument protein UL36; Provisional
      pfam00418
      Location:774 → 803
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P27546.3 GenPept UniProtKB/Swiss-Prot:P27546

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