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    Btg1b BTG anti-proliferation factor 1B [ Mus musculus (house mouse) ]

    Gene ID: 436199, updated on 22-Mar-2024

    Summary

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    Official Symbol
    Btg1bprovided by MGI
    Official Full Name
    BTG anti-proliferation factor 1Bprovided by MGI
    Primary source
    MGI:MGI:3588262
    See related
    Ensembl:ENSMUSG00000121800 AllianceGenome:MGI:3588262
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Btg1-ps1; 4930525M21Rik
    Summary
    Predicted to enable enzyme binding activity. Predicted to be involved in several processes, including positive regulation of angiogenesis; positive regulation of endothelial cell differentiation; and positive regulation of fibroblast apoptotic process. Predicted to be active in cytoplasm and nucleus. Orthologous to human BTG1 (BTG anti-proliferation factor 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 3.0) See more
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    Genomic context

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    See Btg1b in Genome Data Viewer
    Location:
    X A3.3; X 22.27 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (37102050..37107727, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (38013173..38018850, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene reproductive homeobox 11, pseudogene 1 Neighboring gene reproductive homeobox 11, pseudogene 2 Neighboring gene BTG anti-proliferation factor 1C Neighboring gene reproductive homeobox 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. In search of a function for the TIS21/PC3/BTG1/TOB family. Matsuda S, et al. FEBS Lett, 2001 May 25. PMID 11377414
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in negative regulation of cell population proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    B cell translocation gene 1, anti-proliferative-like
    Names
    B cell translocation gene 1, anti-proliferative, pseudogene 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001243943.2 → NP_001230872.1  B cell translocation gene 1, anti-proliferative-like

      See identical proteins and their annotated locations for NP_001230872.1

      Status: VALIDATED

      Source sequence(s)
      AL512346
      Consensus CDS
      CCDS57753.1
      UniProtKB/TrEMBL
      Q3V0S2
      Related
      ENSMUST00000248500.1
      Conserved Domains (1) summary
      pfam07742
      Location:1 → 113
      BTG; BTG family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      37102050..37107727 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006541512.2 → XP_006541575.1  B cell translocation gene 1, anti-proliferative-like isoform X1

      Conserved Domains (1) summary
      pfam07742
      Location:13 → 125
      BTG; BTG family

    2. XM_006541513.2 → XP_006541576.1  B cell translocation gene 1, anti-proliferative-like isoform X2

      See identical proteins and their annotated locations for XP_006541576.1

      UniProtKB/TrEMBL
      Q3V0S2
      Conserved Domains (1) summary
      pfam07742
      Location:1 → 113
      BTG; BTG family
    Nucleotide Protein Strain
    Heading Accession and Version

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