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    Ccdc158 coiled-coil domain containing 158 [ Mus musculus (house mouse) ]

    Gene ID: 320696, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Ccdc158provided by MGI
    Official Full Name
    coiled-coil domain containing 158provided by MGI
    Primary source
    MGI:MGI:2444555
    See related
    Ensembl:ENSMUSG00000050050 AllianceGenome:MGI:2444555
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4932413O14Rik
    Summary
    Orthologous to human CCDC158 (coiled-coil domain containing 158). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 12.5) See more
    Orthologs
    human all
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    Genomic context

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    Location:
    5 E2; 5 47.23 cM
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (92756096..92823327, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (92608237..92675472, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_13648 Neighboring gene family with sequence similarity 47, member E Neighboring gene VISTA enhancer mm187 Neighboring gene starch binding domain 1 Neighboring gene STARR-seq mESC enhancer starr_13649 Neighboring gene shroom family member 3 Neighboring gene STARR-seq mESC enhancer starr_13650 Neighboring gene STARR-seq mESC enhancer starr_13651 Neighboring gene STARR-seq mESC enhancer starr_13653 Neighboring gene microRNA 1961 Neighboring gene STARR-seq mESC enhancer starr_13654 Neighboring gene STARR-seq mESC enhancer starr_13657 Neighboring gene STARR-seq mESC enhancer starr_13658 Neighboring gene VISTA enhancer mm397 Neighboring gene predicted gene, 36764 Neighboring gene ribosomal protein L9 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 158

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360018.1 → NP_001346947.1  coiled-coil domain-containing protein 158 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
      Source sequence(s)
      AC123850, AC124560, BC137976
      UniProtKB/TrEMBL
      B2RQL1
      Conserved Domains (1) summary
      cl25732
      Location:1 → 1113
      SMC_N; RecF/RecN/SMC N terminal domain

    2. NM_001360019.1 → NP_001346948.1  coiled-coil domain-containing protein 158 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, 3' UTR, and 3' coding sequence compared to variant 1. The resulting isoform (c) has a shorter and distinct C-terminus compared to isoform a. Variants 3 and 4 both encode the same isoform (c).
      Source sequence(s)
      AC124560, AK160895
      Consensus CDS
      CCDS89939.1
      Related
      ENSMUSP00000117894.2, ENSMUST00000151180.8
      Conserved Domains (1) summary
      pfam15921
      Location:1 → 342
      CCDC158; Coiled-coil domain-containing protein 158

    3. NM_001360020.1 → NP_001346949.1  coiled-coil domain-containing protein 158 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR, 3' UTR, and 3' coding sequence compared to variant 1. The resulting isoform (c) has a shorter and distinct C-terminus compared to isoform a. Variants 3 and 4 both encode the same isoform (c).
      Source sequence(s)
      AC124560
      Consensus CDS
      CCDS89939.1
      Related
      ENSMUSP00000123259.2, ENSMUST00000150359.2
      Conserved Domains (1) summary
      pfam15921
      Location:1 → 342
      CCDC158; Coiled-coil domain-containing protein 158

    4. NM_177230.3 → NP_796204.1  coiled-coil domain-containing protein 158 isoform b

      See identical proteins and their annotated locations for NP_796204.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
      Source sequence(s)
      AC123850, AC124560
      Consensus CDS
      CCDS19434.1
      UniProtKB/Swiss-Prot
      Q3TU97, Q8CDI6
      Related
      ENSMUSP00000063050.4, ENSMUST00000060930.10
      Conserved Domains (1) summary
      pfam15921
      Location:1 → 1109
      CCDC158; Coiled-coil domain-containing protein 158

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      92756096..92823327 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006534992.4 → XP_006535055.1  coiled-coil domain-containing protein 158 isoform X3

      Conserved Domains (1) summary
      pfam15921
      Location:1 → 1106
      CCDC158; Coiled-coil domain-containing protein 158

    2. XM_030254576.2 → XP_030110436.1  coiled-coil domain-containing protein 158 isoform X7

      Conserved Domains (1) summary
      pfam15921
      Location:1 → 1060
      CCDC158; Coiled-coil domain-containing protein 158

    3. XM_006534994.4 → XP_006535057.1  coiled-coil domain-containing protein 158 isoform X5

      Conserved Domains (1) summary
      pfam15921
      Location:1 → 1077
      CCDC158; Coiled-coil domain-containing protein 158

    4. XM_006534993.4 → XP_006535056.1  coiled-coil domain-containing protein 158 isoform X4

      Conserved Domains (1) summary
      pfam15921
      Location:1 → 1023
      CCDC158; Coiled-coil domain-containing protein 158

    5. XM_006534991.4 → XP_006535054.1  coiled-coil domain-containing protein 158 isoform X2

      Conserved Domains (1) summary
      pfam15921
      Location:1 → 1050
      CCDC158; Coiled-coil domain-containing protein 158

    6. XM_006534996.4 → XP_006535059.1  coiled-coil domain-containing protein 158 isoform X9

      Conserved Domains (1) summary
      pfam15921
      Location:1 → 970
      CCDC158; Coiled-coil domain-containing protein 158

    7. XM_006534989.5 → XP_006535052.1  coiled-coil domain-containing protein 158 isoform X1

      See identical proteins and their annotated locations for XP_006535052.1

      Conserved Domains (1) summary
      pfam15921
      Location:1 → 1054
      CCDC158; Coiled-coil domain-containing protein 158

    8. XM_006534988.4 → XP_006535051.1  coiled-coil domain-containing protein 158 isoform X1

      See identical proteins and their annotated locations for XP_006535051.1

      Conserved Domains (1) summary
      pfam15921
      Location:1 → 1054
      CCDC158; Coiled-coil domain-containing protein 158

    9. XM_006534995.4 → XP_006535058.1  coiled-coil domain-containing protein 158 isoform X6

      Conserved Domains (1) summary
      pfam15921
      Location:1 → 1001
      CCDC158; Coiled-coil domain-containing protein 158

    10. XM_006534997.1 → XP_006535060.1  coiled-coil domain-containing protein 158 isoform X10

      Conserved Domains (1) summary
      pfam15921
      Location:1 → 742
      CCDC158; Coiled-coil domain-containing protein 158

    11. XM_011249479.3 → XP_011247781.1  coiled-coil domain-containing protein 158 isoform X8

      Conserved Domains (1) summary
      pfam15921
      Location:1 → 1053
      CCDC158; Coiled-coil domain-containing protein 158

    12. XM_030254577.2 → XP_030110437.1  coiled-coil domain-containing protein 158 isoform X11

      Conserved Domains (1) summary
      pfam15921
      Location:1 → 342
      CCDC158; Coiled-coil domain-containing protein 158
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8CDI6.1 GenPept UniProtKB/Swiss-Prot:Q8CDI6

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