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    Rmdn1 regulator of microtubule dynamics 1 [ Mus musculus (house mouse) ]

    Gene ID: 66302, updated on 11-Apr-2024

    Summary

    Official Symbol
    Rmdn1provided by MGI
    Official Full Name
    regulator of microtubule dynamics 1provided by MGI
    Primary source
    MGI:MGI:1913552
    See related
    Ensembl:ENSMUSG00000028229 AllianceGenome:MGI:1913552
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RMD-1; Fam82b
    Summary
    Predicted to enable microtubule binding activity. Located in mitochondrion. Orthologous to human RMDN1 (regulator of microtubule dynamics 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in bladder adult (RPKM 3.5), CNS E18 (RPKM 2.9) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    Location:
    4 A3; 4 7.56 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (19575036..19606932)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (19575035..19606932)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene cyclic nucleotide gated channel beta 3 Neighboring gene SET pseudogene Neighboring gene STARR-seq mESC enhancer starr_09695 Neighboring gene STARR-seq mESC enhancer starr_09696 Neighboring gene copine III Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:19502117-19502304 Neighboring gene predicted gene, 52724 Neighboring gene WW domain containing E3 ubiquitin protein ligase 1 Neighboring gene predicted gene 12353 Neighboring gene STARR-positive B cell enhancer ABC_E9583 Neighboring gene STARR-positive B cell enhancer ABC_E2687 Neighboring gene predicted gene 12354

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in mitotic spindle pole IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitotic spindle pole ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in spindle microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in spindle microtubule ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    regulator of microtubule dynamics protein 1
    Names
    family with sequence similarity 82, member B
    microtubule-associated protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025476.6NP_079752.3  regulator of microtubule dynamics protein 1

      See identical proteins and their annotated locations for NP_079752.3

      Status: VALIDATED

      Source sequence(s)
      AK029446, AL683894, BY275756
      Consensus CDS
      CCDS17992.1
      UniProtKB/Swiss-Prot
      A2AGJ3, A9UN01, Q8C0Y9, Q8R166, Q9CWS6, Q9DCV4
      Related
      ENSMUSP00000029888.4, ENSMUST00000029888.4
      Conserved Domains (1) summary
      sd00006
      Location:199249
      TPR; TPR repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      19575036..19606932
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_001784180.3 RNA Sequence

    2. XR_004941945.1 RNA Sequence