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    Wdr93 WD repeat domain 93 [ Mus musculus (house mouse) ]

    Gene ID: 626359, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Wdr93provided by MGI
    Official Full Name
    WD repeat domain 93provided by MGI
    Primary source
    MGI:MGI:3646885
    See related
    Ensembl:ENSMUSG00000039099 AllianceGenome:MGI:3646885
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG626359
    Summary
    Predicted to enable oxidoreductase activity, acting on NAD(P)H. Predicted to be involved in electron transport chain. Predicted to be part of mitochondrial respiratory chain complex I. Orthologous to human WDR93 (WD repeat domain 93). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 11.5), subcutaneous fat pad adult (RPKM 1.7) and 3 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    7 D2; 7 45.13 cM
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (79392897..79435700)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (79742948..79785952)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene perilipin 1 Neighboring gene STARR-positive B cell enhancer mm9_chr7:86873152-86873453 Neighboring gene peroxisomal biogenesis factor 11 alpha Neighboring gene predicted gene 44705 Neighboring gene mesoderm posterior 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in electron transport chain IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial respiratory chain complex I IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    WD repeat-containing protein 93

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037927.1 → NP_001033016.1  WD repeat-containing protein 93 isoform 1

      See identical proteins and their annotated locations for NP_001033016.1

      Status: VALIDATED

      Source sequence(s)
      AB205021
      Consensus CDS
      CCDS39992.1
      UniProtKB/Swiss-Prot
      B9EKH5, Q402B2
      Related
      ENSMUSP00000037467.8, ENSMUST00000035622.8

    2. NM_001381990.1 → NP_001368919.1  WD repeat-containing protein 93 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC109221, AC158582
      UniProtKB/Swiss-Prot
      B9EKH5, Q402B2

    3. NM_001381991.1 → NP_001368920.1  WD repeat-containing protein 93 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC109221, AC158582

    4. NM_001381992.1 → NP_001368921.1  WD repeat-containing protein 93 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC109221, AC158582
      UniProtKB/Swiss-Prot
      B9EKH5, Q402B2

    5. NM_001421522.1 → NP_001408451.1  WD repeat-containing protein 93 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC109221, AC158582
      UniProtKB/Swiss-Prot
      B9EKH5, Q402B2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      79392897..79435700
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030242854.1 → XP_030098714.1  WD repeat-containing protein 93 isoform X1

      UniProtKB/Swiss-Prot
      B9EKH5, Q402B2

    2. XM_036153317.1 → XP_036009210.1  WD repeat-containing protein 93 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q402B2.1 GenPept UniProtKB/Swiss-Prot:Q402B2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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