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    Gtf2i general transcription factor II I [ Mus musculus (house mouse) ]

    Gene ID: 14886, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Gtf2iprovided by MGI
    Official Full Name
    general transcription factor II Iprovided by MGI
    Primary source
    MGI:MGI:1202722
    See related
    Ensembl:ENSMUSG00000060261 AllianceGenome:MGI:1202722
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Spin; Diws1t; TFII-I; WBSCR6; BAP-135; GtfII-I; 6030441I21Rik
    Summary
    Enables mitogen-activated protein kinase binding activity. Acts upstream of or within transition between slow and fast fiber. Located in cell projection; neuronal cell body; and nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; respiratory system; and tooth. Used to study Williams-Beuren syndrome. Orthologous to human GTF2I (general transcription factor IIi). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 36.6), limb E14.5 (RPKM 32.6) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    5 G2; 5 74.48 cM
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (134266686..134346571, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (134237832..134317678, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E105 Neighboring gene STARR-positive B cell enhancer ABC_E4791 Neighboring gene GTF2I repeat domain containing 2 Neighboring gene predicted gene, 57734 Neighboring gene STARR-positive B cell enhancer mm9_chr5:134712733-134713034 Neighboring gene neutrophil cytosolic factor 1 Neighboring gene STARR-positive B cell enhancer ABC_E8084 Neighboring gene STARR-seq mESC enhancer starr_14530 Neighboring gene STARR-seq mESC enhancer starr_14534 Neighboring gene microRNA 3965 Neighboring gene predicted gene, 46925

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Human thymoma-associated mutation of the GTF2I transcription factor impairs thymic epithelial progenitor differentiation in mice. Giorgetti OB, et al. Commun Biol, 2022 Sep 29. PMID 36175547, Free PMC Article
    2. A Knock-In Mouse Model of Thymoma With the GTF2I L424H Mutation. He Y, et al. J Thorac Oncol, 2022 Dec. PMID 36049655, Free PMC Article
    3. TFII-I/Gtf2i and Erythro-Megakaryopoiesis. Gurumurthy A, et al. Front Physiol, 2020. PMID 33101065, Free PMC Article
    4. Mutant GTF2I induces cell transformation and metabolic alterations in thymic epithelial cells. Kim IK, et al. Cell Death Differ, 2020 Jul. PMID 32034314, Free PMC Article
    5. Consistent hypersocial behavior in mice carrying a deletion of Gtf2i but no evidence of hyposocial behavior with Gtf2i duplication: Implications for Williams-Beuren syndrome and autism spectrum disorder. Martin LA, et al. Brain Behav, 2018 Jan. PMID 29568691, Free PMC Article

    See all (91) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Transcription factor TFII-I fine tunes innate properties of B lymphocytes.
      Title: Transcription factor TFII-I fine tunes innate properties of B lymphocytes.
    2. A Knock-In Mouse Model of Thymoma With the GTF2I L424H Mutation.
      Title: A Knock-In Mouse Model of Thymoma With the GTF2I L424H Mutation.
    3. Human thymoma-associated mutation of the GTF2I transcription factor impairs thymic epithelial progenitor differentiation in mice.
      Title: Human thymoma-associated mutation of the GTF2I transcription factor impairs thymic epithelial progenitor differentiation in mice.
    4. Mutant GTF2I induces cell transformation and metabolic alterations in thymic epithelial cells.
      Title: Mutant GTF2I induces cell transformation and metabolic alterations in thymic epithelial cells.
    5. Functions of Gtf2i and Gtf2ird1 in the developing brain: transcription, DNA binding and long-term behavioral consequences.
      Title: Functions of Gtf2i and Gtf2ird1 in the developing brain: transcription, DNA binding and long-term behavioral consequences.
    6. Gtf2i and Gtf2ird1 mutation do not account for the full phenotypic effect of the Williams syndrome critical region in mouse models
      Title: Gtf2i and Gtf2ird1 mutation do not account for the full phenotypic effect of the Williams syndrome critical region in mouse models.
    7. Mice with a single copy of Gtf2i (Gtf2i(+/Del)) had increased axonal outgrowth and increased TRPC3-mediated calcium entry upon carbachol stimulation.
      Title: Transcription Factor 2I Regulates Neuronal Development via TRPC3 in 7q11.23 Disorder Models.
    8. Study provides molecular and cellular evidence for myelination deficits in Williams syndrome linked to neuronal deletion of Gtf2i.
      Title: Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioral and myelin alterations rescuable by a remyelinating drug.
    9. The results suggest a role for GTF2i in the hypersocial phenotype of WBS and more broadly in the regulation of social behavior. Support was not observed for the role of GTF2i in ASD.
      Title: Consistent hypersocial behavior in mice carrying a deletion of Gtf2i but no evidence of hyposocial behavior with Gtf2i duplication: Implications for Williams-Beuren syndrome and autism spectrum disorder.
    10. The Cre-mediated deletion of exon 3 recapitulates a genetic null phenotype, indicating that the conditional Gtf2i line is a valuable tool for studying TFII-I function during embryonic development
      Title: Generation of a mouse model for a conditional inactivation of Gtf2i allele.
    Submit: New GeneRIF Correction See all GeneRIFs (29)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • 6030441I21Rik

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription activator activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II-specific DNA-binding transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of angiogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of cytosolic calcium ion concentration ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    general transcription factor II-I
    Names
    BTK-associated protein 135
    Bruton tyrosine kinase-associated protein 135
    SRF-Phox1-interacting protein
    Williams-Beuren syndrome chromosomal region 6 protein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080746.2 → NP_001074215.1  general transcription factor II-I isoform 1

      See identical proteins and their annotated locations for NP_001074215.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1, also known as Gamma).
      Source sequence(s)
      AC093346, BC053044, CB250008
      Consensus CDS
      CCDS39301.1
      UniProtKB/Swiss-Prot
      O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9, Q9ESZ8
      UniProtKB/TrEMBL
      G3UYD0
      Related
      ENSMUSP00000049625.8, ENSMUST00000059042.15
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    2. NM_001080747.2 → NP_001074216.1  general transcription factor II-I isoform 3

      See identical proteins and their annotated locations for NP_001074216.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (3, also known as Alpha) is shorter than isoform 1.
      Source sequence(s)
      AC093346, BC053044, CB250008
      Consensus CDS
      CCDS39300.1
      UniProtKB/TrEMBL
      G3UYD0
      Related
      ENSMUSP00000080714.4, ENSMUST00000082057.10
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    3. NM_001080748.2 → NP_001074217.1  general transcription factor II-I isoform 4

      See identical proteins and their annotated locations for NP_001074217.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks two alternate in-frame exons in the 5' coding region compared to variant 1. The encoded isoform (4, also known as Delta or Short) is shorter than isoform 1.
      Source sequence(s)
      AC093346, BC053044, CB250008
      Consensus CDS
      CCDS57386.1
      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    4. NM_001080749.2 → NP_001074218.1  general transcription factor II-I isoform 5

      See identical proteins and their annotated locations for NP_001074218.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) lacks two alternate in-frame exons in the 5' coding region and uses an alternate in-frame splice site in the 3' coding region compared to variant 1. The encoded isoform (5) is shorter than isoform 1.
      Source sequence(s)
      AC093346, AK147201, CB250008, MG954273
      Consensus CDS
      CCDS57387.1
      UniProtKB/TrEMBL
      G3UYD0, Q3UHU8
      Related
      ENSMUSP00000133444.2, ENSMUST00000173341.9
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    5. NM_001359062.1 → NP_001345991.1  general transcription factor II-I isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6), as well as variant 1, encodes isoform 1.
      Source sequence(s)
      AC093346, CB250008, MG954273
      Consensus CDS
      CCDS39301.1
      UniProtKB/Swiss-Prot
      O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9, Q9ESZ8
      UniProtKB/TrEMBL
      G3UYD0
      Related
      ENSMUSP00000133566.2, ENSMUST00000174155.8
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    6. NM_001359063.1 → NP_001345992.1  general transcription factor II-I isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7), as well as variants 2 and 8, encodes isoform 2.
      Source sequence(s)
      AC093346, CB250008, MG954273
      Consensus CDS
      CCDS39299.1
      UniProtKB/TrEMBL
      G3UYD0
      Related
      ENSMUSP00000134440.2, ENSMUST00000174354.8
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    7. NM_001359064.1 → NP_001345993.1  general transcription factor II-I isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8), as well as variants 2 and 7, encodes isoform 2.
      Source sequence(s)
      AC093346
      Consensus CDS
      CCDS39299.1
      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    8. NM_001359065.1 → NP_001345994.1  general transcription factor II-I isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9), as well as variant 3, encodes isoform 3.
      Source sequence(s)
      AC093346, CB250008, MG954273
      Consensus CDS
      CCDS39300.1
      UniProtKB/TrEMBL
      G3UYD0
      Related
      ENSMUSP00000133740.2, ENSMUST00000174772.8
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    9. NM_001359066.1 → NP_001345995.1  general transcription factor II-I isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10), as well as variants 4 and 11, encodes isoform 4.
      Source sequence(s)
      AC093346, CB250008, MG954273
      Consensus CDS
      CCDS57386.1
      UniProtKB/TrEMBL
      G3UYD0
      Related
      ENSMUSP00000133489.2, ENSMUST00000174513.8
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    10. NM_001359067.1 → NP_001345996.1  general transcription factor II-I isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11), as well as variant 4 and 10, encodes isoform 4.
      Source sequence(s)
      AC093346
      Consensus CDS
      CCDS57386.1
      UniProtKB/TrEMBL
      G3UYD0
      Related
      ENSMUSP00000133969.2, ENSMUST00000173888.8
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    11. NM_010365.4 → NP_034495.2  general transcription factor II-I isoform 2

      See identical proteins and their annotated locations for NP_034495.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (2, also known as Beta or Long) is shorter than isoform 1.
      Source sequence(s)
      AC093346, BC053044, CB250008
      Consensus CDS
      CCDS39299.1
      UniProtKB/TrEMBL
      G3UYD0
      Related
      ENSMUSP00000106892.5, ENSMUST00000111261.12
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      134266686..134346571 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030254157.2 → XP_030110017.1  general transcription factor II-I isoform X15

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    2. XM_006504386.2 → XP_006504449.1  general transcription factor II-I isoform X4

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    3. XM_006504389.2 → XP_006504452.1  general transcription factor II-I isoform X6

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    4. XM_006504384.2 → XP_006504447.1  general transcription factor II-I isoform X1

      See identical proteins and their annotated locations for XP_006504447.1

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    5. XM_006504385.2 → XP_006504448.1  general transcription factor II-I isoform X3

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    6. XM_030254165.2 → XP_030110025.1  general transcription factor II-I isoform X23

      UniProtKB/TrEMBL
      G3UYD0
      Related
      ENSMUSP00000134035.2, ENSMUST00000172715.8
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    7. XM_030254163.2 → XP_030110023.1  general transcription factor II-I isoform X22

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    8. XM_036164817.1 → XP_036020710.1  general transcription factor II-I isoform X19

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    9. XM_036164818.1 → XP_036020711.1  general transcription factor II-I isoform X20

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    10. XM_030254159.2 → XP_030110019.1  general transcription factor II-I isoform X16

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    11. XM_036164815.1 → XP_036020708.1  general transcription factor II-I isoform X18

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    12. XM_030254161.2 → XP_030110021.1  general transcription factor II-I isoform X21

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    13. XM_036164813.1 → XP_036020706.1  general transcription factor II-I isoform X12

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    14. XM_030254148.2 → XP_030110008.1  general transcription factor II-I isoform X7

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    15. XM_036164810.1 → XP_036020703.1  general transcription factor II-I isoform X9

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    16. XM_030254155.2 → XP_030110015.1  general transcription factor II-I isoform X10

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    17. XM_036164806.1 → XP_036020699.1  general transcription factor II-I isoform X5

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    18. XM_030254147.2 → XP_030110007.1  general transcription factor II-I isoform X2

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    19. XM_030254156.2 → XP_030110016.1  general transcription factor II-I isoform X13

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    20. XM_006504391.2 → XP_006504454.1  general transcription factor II-I isoform X14

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    21. XM_030254153.2 → XP_030110013.1  general transcription factor II-I isoform X8

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    22. XM_017320677.2 → XP_017176166.1  general transcription factor II-I isoform X11

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    23. XM_030254162.2 → XP_030110022.1  general transcription factor II-I isoform X21

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    24. XM_036164803.1 → XP_036020696.1  general transcription factor II-I isoform X2

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    25. XM_030254145.2 → XP_030110005.1  general transcription factor II-I isoform X1

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    26. XM_030254144.2 → XP_030110004.1  general transcription factor II-I isoform X1

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    27. XM_036164808.1 → XP_036020701.1  general transcription factor II-I isoform X7

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    28. XM_036164804.1 → XP_036020697.1  general transcription factor II-I isoform X2

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    29. XM_030254154.2 → XP_030110014.1  general transcription factor II-I isoform X8

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    30. XM_030254146.2 → XP_030110006.1  general transcription factor II-I isoform X1

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    31. XM_036164802.1 → XP_036020695.1  general transcription factor II-I isoform X2

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    32. XM_036164809.1 → XP_036020702.1  general transcription factor II-I isoform X8

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    33. XM_030254140.2 → XP_030110000.1  general transcription factor II-I isoform X1

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    34. XM_030254141.2 → XP_030110001.1  general transcription factor II-I isoform X1

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    35. XM_030254164.2 → XP_030110024.1  general transcription factor II-I isoform X22

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    36. XM_030254158.2 → XP_030110018.1  general transcription factor II-I isoform X15

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    37. XM_036164805.1 → XP_036020698.1  general transcription factor II-I isoform X3

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    38. XM_030254151.2 → XP_030110011.1  general transcription factor II-I isoform X7

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    39. XM_036164814.1 → XP_036020707.1  general transcription factor II-I isoform X12

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    40. XM_036164807.1 → XP_036020700.1  general transcription factor II-I isoform X6

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    41. XM_036164819.1 → XP_036020712.1  general transcription factor II-I isoform X20

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    42. XM_036164816.1 → XP_036020709.1  general transcription factor II-I isoform X18

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    43. XM_017320681.3 → XP_017176170.1  general transcription factor II-I isoform X17

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 184
      GTF2I; GTF2I-like repeat

    44. XM_036164811.1 → XP_036020704.1  general transcription factor II-I isoform X9

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat

    45. XM_036164812.1 → XP_036020705.1  general transcription factor II-I isoform X9

      UniProtKB/TrEMBL
      G3UYD0
      Conserved Domains (1) summary
      pfam02946
      Location:112 → 186
      GTF2I; GTF2I-like repeat
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ESZ8.3 GenPept UniProtKB/Swiss-Prot:Q9ESZ8

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