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    Il18bp interleukin 18 binding protein [ Mus musculus (house mouse) ]

    Gene ID: 16068, updated on 23-Jun-2021

    Summary

    Official Symbol
    Il18bpprovided by MGI
    Official Full Name
    interleukin 18 binding proteinprovided by MGI
    Primary source
    MGI:MGI:1333800
    See related
    Ensembl:ENSMUSG00000070427
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Igi; IL-1; MC54; MC54L; Igifbp; IL-18BP
    Expression
    Ubiquitous expression in thymus adult (RPKM 16.5), liver E18 (RPKM 14.8) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Il18bp in Genome Data Viewer
    Location:
    7; 7 E2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (101664281..101669699, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (102015074..102018232, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (109163591..109166669, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene nuclear mitotic apparatus protein 1 Neighboring gene MYST histone acetyltransferase 1 pseudogene Neighboring gene predicted gene, 39061 Neighboring gene ring finger protein 121 Neighboring gene Xndc1-transient receptor potential cation channel, subfamily C, member 2 readthrough Neighboring gene Xrcc1 N-terminal domain containing 1 Neighboring gene transient receptor potential cation channel, subfamily C, member 2 Neighboring gene ADP-ribosyltransferase 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3) 
    • Endonuclease-mediated (1)  1 citation

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables interleukin-18 binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables interleukin-18 binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in T-helper 1 type immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in T-helper 1 type immune response ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    interleukin-18-binding protein
    Names
    interferon gamma-inducing factor-binding protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001363982.1NP_001350911.1  interleukin-18-binding protein precursor

      Status: VALIDATED

      Source sequence(s)
      AC167240, AK003370
      Consensus CDS
      CCDS21522.1
      Related
      ENSMUSP00000091685.4, ENSMUST00000094134.5
      Conserved Domains (1) summary
      cl23951
      Location:47169
      Pox_vIL-18BP; Orthopoxvirus interleukin 18 binding protein
    2. NM_001382458.1NP_001369387.1  interleukin-18-binding protein precursor

      Status: VALIDATED

      Source sequence(s)
      AC167240
      Conserved Domains (1) summary
      cl23951
      Location:47169
      Pox_vIL-18BP; Orthopoxvirus interleukin 18 binding protein
    3. NM_010531.2NP_034661.1  interleukin-18-binding protein precursor

      See identical proteins and their annotated locations for NP_034661.1

      Status: VALIDATED

      Source sequence(s)
      AC167240, AF122907
      Consensus CDS
      CCDS21522.1
      UniProtKB/Swiss-Prot
      Q9Z0M9
      Related
      ENSMUSP00000148080.2, ENSMUST00000209844.2
      Conserved Domains (1) summary
      cl23951
      Location:47169
      Pox_vIL-18BP; Orthopoxvirus interleukin 18 binding protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      101664281..101669699 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030242160.2XP_030098020.1  interleukin-18-binding protein isoform X2

      Conserved Domains (1) summary
      cl23951
      Location:47169
      Pox_vIL-18BP; Orthopoxvirus interleukin 18 binding protein
    2. XM_036152698.1XP_036008591.1  interleukin-18-binding protein isoform X1

      Related
      ENSMUSP00000148201.2, ENSMUST00000209368.2
      Conserved Domains (1) summary
      cl23951
      Location:47164
      Pox_vIL-18BP; Orthopoxvirus interleukin 18 binding protein
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