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    Dok3 docking protein 3 [ Mus musculus (house mouse) ]

    Gene ID: 27261, updated on 23-Jun-2021

    Summary

    Official Symbol
    Dok3provided by MGI
    Official Full Name
    docking protein 3provided by MGI
    Primary source
    MGI:MGI:1351490
    See related
    Ensembl:ENSMUSG00000035711
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dokl; AI450713
    Expression
    Biased expression in spleen adult (RPKM 71.0), mammary gland adult (RPKM 16.8) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Dok3 in Genome Data Viewer
    Location:
    13; 13 B1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (55671044..55678158, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (55523231..55530345, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (55624596..55629899, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene drebrin 1 Neighboring gene microRNA 6944 Neighboring gene PDZ and LIM domain 7 Neighboring gene microRNA 6945 Neighboring gene DEAD box helicase 41 Neighboring gene predicted gene, 46416 Neighboring gene family with sequence similarity 193, member B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC151299

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    docking protein 3
    Names
    DOK-L
    Dok-like protein
    downstream of tyrosine kinase 3
    p62(dok)-like protein
    p62Dok-like protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013739.2NP_038767.1  docking protein 3

      See identical proteins and their annotated locations for NP_038767.1

      Status: PROVISIONAL

      Source sequence(s)
      CT009762
      Consensus CDS
      CCDS26548.1
      UniProtKB/Swiss-Prot
      Q9QZK7
      UniProtKB/TrEMBL
      Q14AA1
      Related
      ENSMUSP00000046695.5, ENSMUST00000047877.5
      Conserved Domains (2) summary
      cd01203
      Location:157255
      PTB_DOK1_DOK2_DOK3; Downstream of tyrosine kinase 1, 2, and 3 proteins phosphotyrosine-binding domain (PTBi)
      cd14676
      Location:9123
      PH_DOK1,2,3; Pleckstrin homology (PH) domain of Downstream of tyrosine kinase 1, 2, and 3

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      55671044..55678158 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017315524.1XP_017171013.1  docking protein 3 isoform X1

      UniProtKB/Swiss-Prot
      Q9QZK7
      UniProtKB/TrEMBL
      Q14AA1
      Conserved Domains (2) summary
      cd01203
      Location:157255
      PTB_DOK1_DOK2_DOK3; Downstream of tyrosine kinase 1, 2, and 3 proteins phosphotyrosine-binding domain (PTBi)
      cd14676
      Location:9123
      PH_DOK1,2,3; Pleckstrin homology (PH) domain of Downstream of tyrosine kinase 1, 2, and 3
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