U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Ccdc18 coiled-coil domain containing 18 [ Mus musculus (house mouse) ]

    Gene ID: 73254, updated on 5-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Ccdc18provided by MGI
    Official Full Name
    coiled-coil domain containing 18provided by MGI
    Primary source
    MGI:MGI:1922974
    See related
    Ensembl:ENSMUSG00000056531 AllianceGenome:MGI:1922974
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NY-SAR-41; 1700021E15Rik; 4932411G06Rik
    Summary
    Orthologous to human CCDC18 (coiled-coil domain containing 18). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in CNS E11.5 (RPKM 1.3), liver E14 (RPKM 0.9) and 12 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Ccdc18 in Genome Data Viewer
    Location:
    5 F; 5 52.55 cM
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (108280583..108388378)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (108132661..108240512)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_13901 Neighboring gene STARR-seq mESC enhancer starr_13902 Neighboring gene STARR-seq mESC enhancer starr_13904 Neighboring gene metal response element binding transcription factor 2 Neighboring gene STARR-positive B cell enhancer ABC_E2166 Neighboring gene transmembrane p24 trafficking protein 5 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene 8190 Neighboring gene STARR-seq mESC enhancer starr_13907 Neighboring gene predicted gene, 54303 Neighboring gene down-regulator of transcription 1 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class G

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous Kras(G12D). Huang J, et al. Sci Rep, 2019 Nov 20. PMID 31748650, Free PMC Article
    2. TERRA transcripts are bound by a complex array of RNA-binding proteins. López de Silanes I, et al. Nat Commun, 2010 Jun 29. PMID 20975687
    3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

    Go to the top of the page Help

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (2) 

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC100177

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    coiled-coil domain-containing protein 18
    Names
    sarcoma antigen NY-SAR-41
    NP_082757.1
    XP_006535314.1
    XP_006535315.1
    XP_006535316.1
    XP_006535318.1
    XP_036021438.1
    XP_036021439.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028481.1 → NP_082757.1  coiled-coil domain-containing protein 18

      See identical proteins and their annotated locations for NP_082757.1

      Status: PROVISIONAL

      Source sequence(s)
      BC082598
      Consensus CDS
      CCDS39202.1
      UniProtKB/Swiss-Prot
      Q640L5, Q8BIM9, Q8BIN1, Q9DA43
      Related
      ENSMUSP00000036507.8, ENSMUST00000047677.9
      Conserved Domains (2) summary
      COG1196
      Location:512 → 1290
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam04420
      Location:1209 → 1272
      CHD5; CHD5-like protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      108280583..108388378
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006535251.5 → XP_006535314.1  coiled-coil domain-containing protein 18 isoform X1

      See identical proteins and their annotated locations for XP_006535314.1

      Conserved Domains (2) summary
      COG1196
      Location:512 → 1290
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:115 → 888
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    2. XM_006535253.5 → XP_006535316.1  coiled-coil domain-containing protein 18 isoform X2

      Conserved Domains (2) summary
      COG1196
      Location:512 → 1244
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:115 → 888
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    3. XM_036165545.1 → XP_036021438.1  coiled-coil domain-containing protein 18 isoform X4

      Conserved Domains (1) summary
      TIGR02168
      Location:115 → 863
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    4. XM_006535255.5 → XP_006535318.1  coiled-coil domain-containing protein 18 isoform X3

      Conserved Domains (1) summary
      COG1196
      Location:114 → 903
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    5. XM_006535252.5 → XP_006535315.1  coiled-coil domain-containing protein 18 isoform X1

      See identical proteins and their annotated locations for XP_006535315.1

      Conserved Domains (2) summary
      COG1196
      Location:512 → 1290
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:115 → 888
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    6. XM_036165546.1 → XP_036021439.1  coiled-coil domain-containing protein 18 isoform X5

      Conserved Domains (1) summary
      COG1196
      Location:243 → 597
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    RNA

    1. XR_003955715.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q640L5.1 GenPept UniProtKB/Swiss-Prot:Q640L5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous