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    Ect2l epithelial cell transforming sequence 2 oncogene-like [ Mus musculus (house mouse) ]

    Gene ID: 100045792, updated on 8-Mar-2024

    Summary

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    Official Symbol
    Ect2lprovided by MGI
    Official Full Name
    epithelial cell transforming sequence 2 oncogene-likeprovided by MGI
    Primary source
    MGI:MGI:3641723
    See related
    Ensembl:ENSMUSG00000071392 AllianceGenome:MGI:3641723
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm10331; C330021H03Rik
    Summary
    Orthologous to human ECT2L (epithelial cell transforming 2 like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    human all
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    Genomic context

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    See Ect2l in Genome Data Viewer
    Location:
    10 A3; 10 7.47 cM
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (18004123..18086575, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (18128375..18210827, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E5120 Neighboring gene ABRA C-terminal like Neighboring gene RalBP1 associated Eps domain containing protein Neighboring gene STARR-seq mESC enhancer starr_25888 Neighboring gene STARR-seq mESC enhancer starr_25889 Neighboring gene STARR-positive B cell enhancer ABC_E8992 Neighboring gene STARR-positive B cell enhancer mm9_chr10:17930879-17931180 Neighboring gene coiled-coil domain containing 28A Neighboring gene STARR-positive B cell enhancer ABC_E8325 Neighboring gene predicted gene 10827

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    2. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    3. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    4. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article
    5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    epithelial cell-transforming sequence 2 oncogene-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195036.2 → NP_001181965.1  epithelial cell-transforming sequence 2 oncogene-like isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC153433, AC153562
      Consensus CDS
      CCDS56693.1
      UniProtKB/TrEMBL
      A0A140LHP3, F7CKP4
      Related
      ENSMUSP00000093497.5, ENSMUST00000095817.5
      Conserved Domains (4) summary
      pfam00621
      Location:578 → 760
      RhoGEF; RhoGEF domain
      pfam12937
      Location:93 → 130
      F-box-like
      pfam14252
      Location:298 → 467
      DUF4347; Domain of unknown function (DUF4347)
      cl17171
      Location:790 → 910
      PH-like; Pleckstrin homology-like domain

    2. NM_001370991.1 → NP_001357920.1  epithelial cell-transforming sequence 2 oncogene-like isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC153433, AC153562
      Consensus CDS
      CCDS87964.1
      UniProtKB/TrEMBL
      A0A140LHP3, A0A140LIP2
      Related
      ENSMUSP00000146899.2, ENSMUST00000208948.2
      Conserved Domains (4) summary
      pfam00621
      Location:620 → 802
      RhoGEF; RhoGEF domain
      pfam12937
      Location:93 → 130
      F-box-like
      pfam14252
      Location:298 → 467
      DUF4347; Domain of unknown function (DUF4347)
      cl17171
      Location:832 → 952
      PH-like; Pleckstrin homology-like domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      18004123..18086575 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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