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    Gm5150 predicted gene 5150 [ Mus musculus (house mouse) ]

    Gene ID: 381484, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Gm5150provided by MGI
    Official Full Name
    predicted gene 5150provided by MGI
    Primary source
    MGI:MGI:3779469
    See related
    Ensembl:ENSMUSG00000078780 AllianceGenome:MGI:3779469
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be involved in positive regulation of T cell activation and positive regulation of phagocytosis. Predicted to be active in plasma membrane. Orthologous to human SIRPB2 (signal regulatory protein beta 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    Location:
    3 A1; 3 3.91 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (16001035..16060535, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (15946871..16006371, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_07028 Neighboring gene eukaryotic translation initiation factor 3, subunit M pseudogene Neighboring gene STARR-seq mESC enhancer starr_07029 Neighboring gene STARR-seq mESC enhancer starr_07030 Neighboring gene phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase pseudogene Neighboring gene STARR-seq mESC enhancer starr_07031 Neighboring gene STARR-seq mESC enhancer starr_07032 Neighboring gene STARR-seq mESC enhancer starr_07033 Neighboring gene STARR-seq mESC enhancer starr_07034 Neighboring gene STARR-seq mESC enhancer starr_07036 Neighboring gene STARR-seq mESC enhancer starr_07037 Neighboring gene STARR-positive B cell enhancer ABC_E2660 Neighboring gene STARR-seq mESC enhancer starr_07038 Neighboring gene STARR-seq mESC enhancer starr_07039 Neighboring gene STARR-seq mESC enhancer starr_07040 Neighboring gene STARR-seq mESC enhancer starr_07041 Neighboring gene YTH N6-methyladenosine RNA binding protein 3 Neighboring gene STARR-seq mESC enhancer starr_07042 Neighboring gene STARR-seq mESC enhancer starr_07043 Neighboring gene STARR-seq mESC enhancer starr_07044 Neighboring gene STARR-seq mESC enhancer starr_07045 Neighboring gene STARR-seq mESC enhancer starr_07046 Neighboring gene STARR-seq mESC enhancer starr_07050 Neighboring gene STARR-seq mESC enhancer starr_07051 Neighboring gene STARR-seq mESC enhancer starr_07052 Neighboring gene STARR-seq mESC enhancer starr_07053 Neighboring gene STARR-seq mESC enhancer starr_07054 Neighboring gene STARR-seq mESC enhancer starr_07055 Neighboring gene predicted gene, 30223 Neighboring gene predicted gene, 26485

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Signal regulatory protein molecules are differentially expressed by CD8- dendritic cells. Lahoud MH, et al. J Immunol, 2006 Jul 1. PMID 16785533
    2. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of T cell activation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of phagocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC381484
    Names
    SIRP beta 1 like 1 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081687.1 → NP_001075156.1  uncharacterized protein LOC381484 precursor

      See identical proteins and their annotated locations for NP_001075156.1

      Status: PREDICTED

      Source sequence(s)
      DQ055451
      Consensus CDS
      CCDS38395.1
      UniProtKB/TrEMBL
      Q1AN92
      Related
      ENSMUSP00000103984.3, ENSMUST00000108347.3
      Conserved Domains (1) summary
      cl11960
      Location:32 → 143
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      16001035..16060535 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163147.1 → XP_036019040.1  uncharacterized protein LOC381484 isoform X3

      Conserved Domains (2) summary
      cd00096
      Location:32 → 35
      Ig; Ig strand A [structural motif]
      cl11960
      Location:32 → 143
      Ig; Immunoglobulin domain

    2. XM_006535488.1 → XP_006535551.1  uncharacterized protein LOC381484 isoform X4

      Conserved Domains (1) summary
      cl11960
      Location:32 → 143
      Ig; Immunoglobulin domain

    3. XM_006535485.1 → XP_006535548.1  uncharacterized protein LOC381484 isoform X1

      See identical proteins and their annotated locations for XP_006535548.1

      UniProtKB/TrEMBL
      Q1AN92
      Related
      ENSMUSP00000141397.2, ENSMUST00000194367.6
      Conserved Domains (1) summary
      cl11960
      Location:32 → 143
      Ig; Immunoglobulin domain

    4. XM_011249685.1 → XP_011247987.1  uncharacterized protein LOC381484 isoform X2

      Conserved Domains (1) summary
      cl11960
      Location:32 → 143
      Ig; Immunoglobulin domain

    RNA

    1. XR_389592.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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