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    Glod5 glyoxalase domain containing 5 [ Mus musculus (house mouse) ]

    Gene ID: 69824, updated on 25-Apr-2024

    Summary

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    Official Symbol
    Glod5provided by MGI
    Official Full Name
    glyoxalase domain containing 5provided by MGI
    Primary source
    MGI:MGI:1917074
    See related
    Ensembl:ENSMUSG00000031163 AllianceGenome:MGI:1917074
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2010001H14Rik
    Summary
    Is expressed in lung and pituitary gland. Orthologous to human GLOD5 (glyoxalase domain containing 5). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in large intestine adult (RPKM 22.1), kidney adult (RPKM 8.7) and 3 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Glod5 in Genome Data Viewer
    Location:
    X A1.1; X 3.61 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (7870440..7884731, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (8004201..8018492, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 39488 Neighboring gene proteasome (prosome, macropain) subunit, beta type 6, pseudogene Neighboring gene GATA binding protein 1 Neighboring gene predicted gene, 52419 Neighboring gene STARR-seq mESC enhancer starr_46683 Neighboring gene STARR-seq mESC enhancer starr_46684 Neighboring gene ribosomal protein L22, pseudogene 1 Neighboring gene oxidative stress-responsive serine-rich protein 1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Phenotypic annotation of the mouse X chromosome. Cox BJ, et al. Genome Res, 2010 Aug. PMID 20548051, Free PMC Article
    2. Mutagenesis of diploid mammalian genes by gene entrapment. Lin Q, et al. Nucleic Acids Res, 2006. PMID 17062627, Free PMC Article
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    glyoxalase domain-containing protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027227.2 → NP_081503.1  glyoxalase domain-containing protein 5

      See identical proteins and their annotated locations for NP_081503.1

      Status: VALIDATED

      Source sequence(s)
      AK008008
      Consensus CDS
      CCDS29982.1
      UniProtKB/Swiss-Prot
      Q9D8I3
      Related
      ENSMUSP00000033503.3, ENSMUST00000033503.3
      Conserved Domains (1) summary
      cd07253
      Location:23 → 145
      Glo_EDI_BRP_like_2; This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      7870440..7884731 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527699.4 → XP_006527762.1  glyoxalase domain-containing protein 5 isoform X1

      Conserved Domains (1) summary
      cd07253
      Location:1 → 115
      GLOD5; Human glyoxalase domain-containing protein 5 and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D8I3.1 GenPept UniProtKB/Swiss-Prot:Q9D8I3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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