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    Glcci1 glucocorticoid induced 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296884, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Glcci1provided by RGD
    Official Full Name
    glucocorticoid induced 1provided by RGD
    Primary source
    RGD:1563612
    See related
    Ensembl:ENSRNOG00000008524 AllianceGenome:RGD:1563612
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563612
    Summary
    Predicted to be active in cytoplasm. Orthologous to human GLCCI1 (glucocorticoid induced 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 772.8), Brain (RPKM 82.6) and 4 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    4q21
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (37274271..37601898)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (36307956..36635614)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (34282625..34612709)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486727 Neighboring gene meiosis regulator for oocyte development Neighboring gene replication protein A3 Neighboring gene islet cell autoantigen 1 Neighboring gene uncharacterized LOC102550643 Neighboring gene neurexophilin 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. GLCCI1 is a novel component associated with the PI3K signaling pathway in podocyte foot processes. Kim SH, et al. Exp Mol Med, 2016 May 13. PMID 27174202, Free PMC Article
    2. Two genes, three messengers: hybrid transcript between a gene expressed at specific stages of T-cell and sperm maturation and an unrelated adjacent gene. Miazek A, et al. Immunogenetics, 2003 Jan. PMID 12557054
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. GLCCI1 is a novel component associated with the PI3K signaling pathway in podocyte foot processes
      Title: GLCCI1 is a novel component associated with the PI3K signaling pathway in podocyte foot processes.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    glucocorticoid-induced transcript 1 protein
    Names
    glucocorticoid induced transcript 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001177442.1 → NP_001170913.1  glucocorticoid-induced transcript 1 protein precursor

      See identical proteins and their annotated locations for NP_001170913.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473959
      UniProtKB/TrEMBL
      A0A0G2JU60, B2RYK0
      Related
      ENSRNOP00000068976.2, ENSRNOT00000086735.2
      Conserved Domains (1) summary
      pfam15388
      Location:51 → 360
      FAM117; Protein Family FAM117

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      37274271..37601898
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039107260.2 → XP_038963188.1  glucocorticoid-induced transcript 1 protein isoform X1

      UniProtKB/TrEMBL
      A0A8I6ACU6
      Related
      ENSRNOP00000091830.1
      Conserved Domains (1) summary
      pfam15388
      Location:154 → 464
      FAM117; Protein Family FAM117

    2. XM_039107262.2 → XP_038963190.1  glucocorticoid-induced transcript 1 protein isoform X3

      Conserved Domains (1) summary
      pfam15388
      Location:154 → 389
      FAM117; Protein Family FAM117

    3. XM_039107261.2 → XP_038963189.1  glucocorticoid-induced transcript 1 protein isoform X2

      Conserved Domains (1) summary
      pfam15388
      Location:154 → 463
      FAM117; Protein Family FAM117

    4. XM_063285724.1 → XP_063141794.1  glucocorticoid-induced transcript 1 protein isoform X4

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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