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    CG31717 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318911, updated on 4-Apr-2024

    Summary

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    Official Symbol
    CG31717provided by FlyBase
    Primary source
    FLYBASE:FBgn0051717
    Locus tag
    Dmel_CG31717
    See related
    AllianceGenome:FB:FBgn0051717
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT30094; Css2; Dmel\CG31717
    Summary
    Predicted to enable sphingosine-1-phosphate phosphatase activity. Predicted to be involved in phospholipid dephosphorylation. Predicted to be active in membrane. Is expressed in adult head. Orthologous to several human genes including PLPP7 (phospholipid phosphatase 7 (inactive)). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See CG31717 in Genome Data Viewer
    Location:
    31B1-31B1; 2-40 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10250737..10251714)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10250737..10251714)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44995 Neighboring gene chico Neighboring gene basket Neighboring gene Ror Neighboring gene uncharacterized protein Neighboring gene Phosphatase and tensin homolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila mojavensis - chico. Congleton H, et al. MicroPubl Biol, 2022. PMID 36468157, Free PMC Article
    2. Identification of a family of animal sphingomyelin synthases. Huitema K, et al. EMBO J, 2004 Jan 14. PMID 14685263, Free PMC Article
    3. Genome-wide identification of phospho-regulators of Wnt signaling in Drosophila. Swarup S, et al. Development, 2015 Apr 15. PMID 25852200
    4. Automated identification of putative methyltransferases from genomic open reading frames. Katz JE, et al. Mol Cell Proteomics, 2003 Aug. PMID 12872006
    5. Genome-wide analyses of Shavenbaby target genes reveals distinct features of enhancer organization. Menoret D, et al. Genome Biol, 2013 Aug 23. PMID 23972280, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables sphingosine-1-phosphate phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in phospholipid dephosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31717-PA
    CG31717-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10250737..10251714
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164902.2 → NP_723543.1  uncharacterized protein Dmel_CG31717, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723543.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T8T9
      Related
      FBpp0079567
      Conserved Domains (2) summary
      COG0671
      Location:49 → 182
      PgpB; Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]
      cd03391
      Location:23 → 179
      PAP2_containing_2_like; PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a ...

    2. NM_001273388.1 → NP_001260317.1  uncharacterized protein Dmel_CG31717, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260317.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T8T9
      Conserved Domains (2) summary
      COG0671
      Location:49 → 182
      PgpB; Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]
      cd03391
      Location:23 → 179
      PAP2_containing_2_like; PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T8T9 Q8T8T9

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