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    Btbd17 BTB domain containing 17 [ Mus musculus (house mouse) ]

    Gene ID: 72014, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Btbd17provided by MGI
    Official Full Name
    BTB domain containing 17provided by MGI
    Primary source
    MGI:MGI:1919264
    See related
    Ensembl:ENSMUSG00000000202 AllianceGenome:MGI:1919264
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tango10a; 1500005I02Rik
    Summary
    Predicted to be located in extracellular region. Is expressed in central nervous system; intestine; liver; olfactory epithelium; and retina. Orthologous to human BTBD17 (BTB domain containing 17). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in cerebellum adult (RPKM 8.0), CNS E11.5 (RPKM 7.0) and 8 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Btbd17 in Genome Data Viewer
    Location:
    11 E2; 11 80.54 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (114681495..114692738, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (114790669..114801916, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene tweety family member 2 Neighboring gene STARR-positive B cell enhancer mm9_chr11:114606533-114606834 Neighboring gene dynein axonemal intermediate chain 2 Neighboring gene kinesin family member 19A Neighboring gene G protein-coupled receptor 142 Neighboring gene G protein-coupled receptor, family C, group 5, member C Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:114734569-114734722 Neighboring gene STARR-seq mESC enhancer starr_31138 Neighboring gene CD300A molecule

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Single-cell transcriptomic analysis of mouse neocortical development. Loo L, et al. Nat Commun, 2019 Jan 11. PMID 30635555, Free PMC Article
    2. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
    3. ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease. Cozzolino F, et al. Hum Mol Genet, 2021 Jun 17. PMID 33601422
    4. Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant. Quinlan MA, et al. Front Mol Neurosci, 2020. PMID 32581705, Free PMC Article
    5. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    BTB/POZ domain-containing protein 17
    Names
    BTB (POZ) domain containing 17

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028055.4 → NP_082331.1  BTB/POZ domain-containing protein 17 precursor

      See identical proteins and their annotated locations for NP_082331.1

      Status: PROVISIONAL

      Source sequence(s)
      AL663079
      Consensus CDS
      CCDS25610.1
      UniProtKB/Swiss-Prot
      Q9DB72
      Related
      ENSMUSP00000000206.4, ENSMUST00000000206.4
      Conserved Domains (3) summary
      smart00225
      Location:64 → 162
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00875
      Location:169 → 267
      BACK; BTB And C-terminal Kelch
      pfam00651
      Location:63 → 158
      BTB; BTB/POZ domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      114681495..114692738 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006534280.2 → XP_006534343.1  BTB/POZ domain-containing protein 17 isoform X4

      See identical proteins and their annotated locations for XP_006534343.1

      Conserved Domains (2) summary
      cd18493
      Location:119 → 191
      BACK_BTBD17; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 17 (BTBD17)
      cl38908
      Location:13 → 111
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

    2. XM_017314777.1 → XP_017170266.1  BTB/POZ domain-containing protein 17 isoform X1

      Conserved Domains (2) summary
      cd18493
      Location:173 → 245
      BACK_BTBD17; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 17 (BTBD17)
      cl38908
      Location:67 → 165
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

    3. XM_006534278.4 → XP_006534341.1  BTB/POZ domain-containing protein 17 isoform X2

      Conserved Domains (2) summary
      cd18292
      Location:46 → 156
      BTB_POZ_BTBD17; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 17 (BTBD17)
      cd18493
      Location:164 → 236
      BACK_BTBD17; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 17 (BTBD17)

    4. XM_017314778.3 → XP_017170267.1  BTB/POZ domain-containing protein 17 isoform X3

      Conserved Domains (2) summary
      cd18493
      Location:144 → 216
      BACK_BTBD17; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 17 (BTBD17)
      cl38908
      Location:38 → 136
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9DB72.1 GenPept UniProtKB/Swiss-Prot:Q9DB72

    Gene LinkOut

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