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    WAKL2 wall associated kinase-like 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838182, updated on 15-Feb-2024

    Summary

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    Gene symbol
    WAKL2
    Gene description
    wall associated kinase-like 2
    Primary source
    Araport:AT1G16130
    Locus tag
    AT1G16130
    See related
    TAIR:AT1G16130
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T24D18.21; T24D18_21; wall associated kinase-like 2
    Summary
    wall-associated kinase like
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    Genomic context

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    See WAKL2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (5525293..5528212)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene wall associated kinase-like 6 Neighboring gene ncRNA Neighboring gene wall associated kinase-like 1 Neighboring gene miscRNA Neighboring gene wall associated kinase-like 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tissue-specific and developmentally regulated expression of a cluster of tandemly arrayed cell wall-associated kinase-like kinase genes in Arabidopsis. Verica JA, et al. Plant Physiol, 2003 Dec. PMID 14576286, Free PMC Article
    2. Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system. Nemoto K, et al. Phytochemistry, 2011 Jul. PMID 21477822
    3. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    4. Multi-omics network-based functional annotation of unknown Arabidopsis genes. Depuydt T, et al. Plant J, 2021 Nov. PMID 34562334
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_101480.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables polysaccharide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity HDA PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein autophosphorylation HDA PubMed 
    Component Evidence Code Pubs
    located_in plant-type cell wall ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    wall associated kinase-like 2
    NP_173064.1
    • wall associated kinase-like 2 (WAKL2); FUNCTIONS IN: kinase activity; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: integral to membrane; EXPRESSED IN: stem, cotyledon, leaf whorl, leaf; EXPRESSED DURING: LP.06 six leaves visible, LP.04 four leaves visible, LP.10 ten leaves visible, LP.08 eight leaves visible, LP.12 twelve leaves visible; CONTAINS InterPro DOMAIN/s: Wall-associated kinase (InterPro:IPR013695), EGF-like calcium-binding, conserved site (InterPro:IPR018097), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: wall associated kinase-like 4 (TAIR:AT1G16150.1); Has 122559 Blast hits to 120935 proteins in 4599 species: Archae - 125; Bacteria - 14250; Metazoa - 44921; Fungi - 10430; Plants - 34238; Viruses - 502; Other Eukaryotes - 18093 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      5525293..5528212
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101480.3 → NP_173064.1  wall associated kinase-like 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173064.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7X8C5, Q9S9M4
      UniProtKB/TrEMBL
      A0A178W6T3
      Conserved Domains (4) summary
      smart00219
      Location:418 → 686
      TyrKc; Tyrosine kinase, catalytic domain
      pfam08488
      Location:168 → 274
      WAK; Wall-associated kinase
      cd14066
      Location:422 → 687
      STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
      pfam13947
      Location:32 → 136
      GUB_WAK_bind; Wall-associated receptor kinase galacturonan-binding
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7X8C5.1

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