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    Tvp23b trans-golgi network vesicle protein 23 homolog B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 687358, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Tvp23bprovided by RGD
    Official Full Name
    trans-golgi network vesicle protein 23 homolog Bprovided by RGD
    Primary source
    RGD:1586539
    See related
    Ensembl:ENSRNOG00000050649 AllianceGenome:RGD:1586539
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam18b2
    Summary
    Predicted to be involved in protein secretion and vesicle-mediated transport. Predicted to be integral component of Golgi membrane. Orthologous to human TVP23B (trans-golgi network vesicle protein 23 homolog B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 301.4), Liver (RPKM 275.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    10q23
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (48053005..48067326)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (47553789..47565203)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (49299125..49312814)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene tripartite motif-containing 16 Neighboring gene F-box and WD repeat domain containing 10 Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC120095116 Neighboring gene uncharacterized LOC102552952

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC187848

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in protein secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Golgi apparatus membrane protein TVP23 homolog B
    Names
    family with sequence similarity 18, member B2
    trans-golgi network vesicle protein 23 B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107568.3 → NP_001101038.2  Golgi apparatus membrane protein TVP23 homolog B

      See identical proteins and their annotated locations for NP_001101038.2

      Status: VALIDATED

      Source sequence(s)
      BC168178, CK483802
      UniProtKB/TrEMBL
      A6HFC7, A6HFC9, M0R766
      Related
      ENSRNOP00000065284.1, ENSRNOT00000074853.2
      Conserved Domains (1) summary
      pfam05832
      Location:32 → 174
      DUF846; Eukaryotic protein of unknown function (DUF846)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      48053005..48067326
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039086835.2 → XP_038942763.1  Golgi apparatus membrane protein TVP23 homolog B isoform X1

      Conserved Domains (1) summary
      pfam05832
      Location:32 → 154
      DUF846; Eukaryotic protein of unknown function (DUF846)

    2. XM_017597529.3 → XP_017453018.1  Golgi apparatus membrane protein TVP23 homolog B isoform X2

    RNA

    1. XR_010055246.1 RNA Sequence

    2. XR_010055248.1 RNA Sequence

    3. XR_010055245.1 RNA Sequence

    4. XR_010055249.1 RNA Sequence

    5. XR_010055250.1 RNA Sequence

    6. XR_010055247.1 RNA Sequence

    7. XR_010055252.1 RNA Sequence

    8. XR_010055251.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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