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    PIP2E plasma membrane intrinsic protein 2E [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818487, updated on 15-Feb-2024

    Summary

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    Gene symbol
    PIP2E
    Gene description
    plasma membrane intrinsic protein 2E
    Primary source
    Araport:AT2G39010
    Locus tag
    AT2G39010
    See related
    TAIR:AT2G39010
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    PIP2;6; PLASMA MEMBRANE INTRINSIC PROTEIN 2;6; plasma membrane intrinsic protein 2E; T7F6.18; T7F6_18
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    Genomic context

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    See PIP2E in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (16291280..16294101)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Acyl-CoA N-acyltransferases (NAT) superfamily protein Neighboring gene ncRNA Neighboring gene Acyl-CoA N-acyltransferases (NAT) superfamily protein Neighboring gene Acyl-CoA N-acyltransferases (NAT) superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Enhanced Boron Tolerance in Plants Mediated by Bidirectional Transport Through Plasma Membrane Intrinsic Proteins. Mosa KA, et al. Sci Rep, 2016 Feb 23. PMID 26902738, Free PMC Article
    2. The major intrinsic protein family of Arabidopsis has 23 members that form three distinct groups with functional aquaporins in each group. Weig A, et al. Plant Physiol, 1997 Aug. PMID 9276952, Free PMC Article
    3. The Arabidopsis abiotic stress-induced TSPO-related protein reduces cell-surface expression of the aquaporin PIP2;7 through protein-protein interactions and autophagic degradation. Hachez C, et al. Plant Cell, 2014 Dec. PMID 25538184, Free PMC Article
    4. Nematode-induced changes of transporter gene expression in Arabidopsis roots. Hammes UZ, et al. Mol Plant Microbe Interact, 2005 Dec. PMID 16478044
    5. Novel Aquaporin Regulatory Mechanisms Revealed by Interactomics. Bellati J, et al. Mol Cell Proteomics, 2016 Nov. PMID 27609422, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Enhanced boron tolerance is mediated by bidirectional transport through plasma membrane aquaporins, PIP1;3 and PIP2;6.
      Title: Enhanced Boron Tolerance in Plants Mediated by Bidirectional Transport Through Plasma Membrane Intrinsic Proteins.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_129458.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables water channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to nematode HEP PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within water transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    plasma membrane intrinsic protein 2E
    NP_181434.1
    • plasma membrane intrinsic protein 2E (PIP2E); FUNCTIONS IN: water channel activity; INVOLVED IN: transport, response to nematode; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Aquaporin (InterPro:IPR012269), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: plasma membrane intrinsic protein 2;5 (TAIR:AT3G54820.1); Has 10794 Blast hits to 10789 proteins in 2219 species: Archae - 81; Bacteria - 5177; Metazoa - 1475; Fungi - 441; Plants - 2519; Viruses - 2; Other Eukaryotes - 1099 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      16291280..16294101
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001336755.1 → NP_001324169.1  plasma membrane intrinsic protein 2E [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AZD1
      Conserved Domains (1) summary
      cl00200
      Location:30 → 200
      MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...

    2. NM_129458.3 → NP_181434.1  plasma membrane intrinsic protein 2E [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181434.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZV07
      UniProtKB/TrEMBL
      A0A178VZ30, A0A5S9X595, A0A7G2EIR5
      Conserved Domains (1) summary
      pfam00230
      Location:30 → 265
      MIP; Major intrinsic protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZV07.1

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