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    Plcxd2 phosphatidylinositol-specific phospholipase C, X domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363781, updated on 4-Apr-2024

    Summary

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    Official Symbol
    Plcxd2provided by RGD
    Official Full Name
    phosphatidylinositol-specific phospholipase C, X domain containing 2provided by RGD
    Primary source
    RGD:1563504
    See related
    Ensembl:ENSRNOG00000042289 AllianceGenome:RGD:1563504
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563504
    Summary
    Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid metabolic process. Orthologous to human PLCXD2 (phosphatidylinositol specific phospholipase C X domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 176.1), Kidney (RPKM 37.0) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Plcxd2 in Genome Data Viewer
    Location:
    11q21
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (68263626..68315962)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (54800977..54853348)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (57207656..57260001)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein A1, pseudogene 30 Neighboring gene CD96 molecule Neighboring gene zinc finger, BED-type containing 2, pseudogene 1 Neighboring gene pleckstrin homology-like domain, family B, member 2 Neighboring gene uncharacterized LOC102552450 Neighboring gene small nucleolar RNA U13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables phosphoric diester hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    PI-PLC X domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134481.3 → NP_001127953.1  PI-PLC X domain-containing protein 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A6IQX1, D4A4P6
      Related
      ENSRNOP00000073045.1, ENSRNOT00000085754.2
      Conserved Domains (1) summary
      cd08616
      Location:39 → 329
      PI-PLCXD1c; Catalytic domain of phosphatidylinositol-specific phospholipase C, X domain containing 1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      68263626..68315962
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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