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    Tmem182 transmembrane protein 182 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 501129, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Tmem182provided by RGD
    Official Full Name
    transmembrane protein 182provided by RGD
    Primary source
    RGD:1563696
    See related
    Ensembl:ENSRNOG00000028945 AllianceGenome:RGD:1563696
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563696
    Summary
    Predicted to be integral component of membrane. Orthologous to human TMEM182 (transmembrane protein 182). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Heart (RPKM 857.4), Muscle (RPKM 807.6) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem182 in Genome Data Viewer
    Location:
    9q22
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (50555029..50606908)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (43059432..43111318)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (47536824..47588677)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103690525 Neighboring gene solute carrier family 9 member A2 Neighboring gene major facilitator superfamily domain containing 9 Neighboring gene uncharacterized LOC120094676 Neighboring gene uncharacterized LOC134480364

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in muscle organ development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in myotube cell development involved in skeletal muscle regeneration ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in myotube differentiation involved in skeletal muscle regeneration ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of myoblast differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of myoblast fusion ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 182

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109305.1 → NP_001102775.1  transmembrane protein 182

      See identical proteins and their annotated locations for NP_001102775.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473965
      UniProtKB/TrEMBL
      A6INP7
      Conserved Domains (1) summary
      pfam13903
      Location:15 → 220
      Claudin_2; PMP-22/EMP/MP20/Claudin tight junction

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      50555029..50606908
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039084079.1 → XP_038940007.1  transmembrane protein 182 isoform X2

      UniProtKB/TrEMBL
      D3ZZT3
      Conserved Domains (1) summary
      cl21598
      Location:13 → 167
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    2. XM_039084081.2 → XP_038940009.1  transmembrane protein 182 isoform X4

      Conserved Domains (1) summary
      cl21598
      Location:15 → 110
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    3. XM_039084077.1 → XP_038940005.1  transmembrane protein 182 isoform X1

      Conserved Domains (1) summary
      cl21598
      Location:15 → 174
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    4. XM_039084078.2 → XP_038940006.1  transmembrane protein 182 isoform X2

      UniProtKB/TrEMBL
      D3ZZT3
      Related
      ENSRNOP00000049496.4
      Conserved Domains (1) summary
      cl21598
      Location:13 → 167
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    5. XM_039084080.2 → XP_038940008.1  transmembrane protein 182 isoform X3

      Conserved Domains (1) summary
      cl21598
      Location:58 → 121
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
    Nucleotide Protein Strain
    Heading Accession and Version

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