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    CG15120 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37248, updated on 10-May-2024

    Summary

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    Official Symbol
    CG15120provided by FlyBase
    Primary source
    FLYBASE:FBgn0034454
    Locus tag
    Dmel_CG15120
    See related
    AllianceGenome:FB:FBgn0034454
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG15120
    Summary
    Predicted to enable chaperone binding activity; heat shock protein binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in negative regulation of cell death. Predicted to be located in cytosol and nucleus. Orthologous to human PACRG (parkin coregulated). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG15120 in Genome Data Viewer
    Location:
    56D13-56D14; 2-89 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19497752..19500372)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15385257..15387877)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Outer segment 6 Neighboring gene Rab escort protein Neighboring gene hippo Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44472 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of Drosophila mutants altering defense of and endurance to Listeria monocytogenes infection. Ayres JS, et al. Genetics, 2008 Mar. PMID 18245331, Free PMC Article
    2. Inactivation of Hippo and cJun-N-terminal Kinase (JNK) signaling mitigate FUS mediated neurodegeneration in vivo. Gogia N, et al. Neurobiol Dis, 2020 Jul. PMID 32199908, Free PMC Article
    3. Decoding cilia function: defining specialized genes required for compartmentalized cilia biogenesis. Avidor-Reiss T, et al. Cell, 2004 May 14. PMID 15137945
    4. Reproductive status alters transcriptomic response to infection in female Drosophila melanogaster. Short SM, et al. G3 (Bethesda), 2013 May 20. PMID 23550122, Free PMC Article
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables Hsp70 protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables Hsp90 protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin protein ligase binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15120-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      19497752..19500372
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137584.3 → NP_611428.1  uncharacterized protein Dmel_CG15120 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611428.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBM4, C0HDN9
      Related
      FBpp0085659
      Conserved Domains (1) summary
      pfam10274
      Location:121 → 304
      ParcG; Parkin co-regulated protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZBM4 A1ZBM4
    Q8MZ25 Q8MZ25

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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