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    l(1)G0289 lethal (1) G0289 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31964, updated on 4-Apr-2024

    Summary

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    Official Symbol
    l(1)G0289provided by FlyBase
    Official Full Name
    lethal (1) G0289provided by FlyBase
    Primary source
    FLYBASE:FBgn0028331
    Locus tag
    Dmel_CG2221
    See related
    AllianceGenome:FB:FBgn0028331
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2221; Dmel\CG2221; Mgn1457
    Summary
    Is expressed in several structures, including anlage in statu nascendi; embryonic/larval muscle system; epithelium; gonad; and gut section. Orthologous to several human genes including PLXDC1 (plexin domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    9B7-9B12; 1-31 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10348680..10366273, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10250862..10260306, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Overlapping but Distinct Sequences Play Roles in the Insulator and Promoter Activities of the Drosophila BEAF-Dependent scs' Insulator. Maharjan M, et al. Genetics, 2020 Aug. PMID 32554599, Free PMC Article
    2. Cis-regulatory variation is typically polyallelic in Drosophila. Gruber JD, et al. Genetics, 2009 Feb. PMID 19064705, Free PMC Article
    3. Quantitative and molecular genetic analyses of mutations increasing Drosophila life span. Magwire MM, et al. PLoS Genet, 2010 Jul 29. PMID 20686706, Free PMC Article
    4. Diversity and dynamics of the Drosophila transcriptome. Brown JB, et al. Nature, 2014 Aug 28. PMID 24670639, Free PMC Article
    5. Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function. Lécuyer E, et al. Cell, 2007 Oct 5. PMID 17923096

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    lethal (1) G0289
    Names
    CG2221-PA
    CG2221-PB
    CG2221-PC
    CG2221-PD
    l(1)G0289-PA
    l(1)G0289-PB
    l(1)G0289-PC
    l(1)G0289-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      10348680..10366273 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001316627.1 → NP_001303556.1  lethal (1) G0289, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2V9
      Conserved Domains (1) summary
      pfam01437
      Location:421 → 477
      PSI; Plexin repeat

    2. NM_132393.3 → NP_572621.1  lethal (1) G0289, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572621.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2V9
      Related
      FBpp0071404
      Conserved Domains (1) summary
      pfam01437
      Location:421 → 477
      PSI; Plexin repeat

    3. NM_001414066.1 → NP_001401057.1  lethal (1) G0289, isoform D [Drosophila melanogaster]

      Status: REVIEWED

    4. NM_001316626.1 → NP_001303555.1  lethal (1) G0289, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2V9
      Conserved Domains (1) summary
      pfam01437
      Location:421 → 477
      PSI; Plexin repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W2V9 Q9W2V9

    Gene LinkOut

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