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    Rnf215 ring finger protein 215 [ Mus musculus (house mouse) ]

    Gene ID: 71673, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Rnf215provided by MGI
    Official Full Name
    ring finger protein 215provided by MGI
    Primary source
    MGI:MGI:1918923
    See related
    Ensembl:ENSMUSG00000003581 AllianceGenome:MGI:1918923
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0610009J22Rik
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in Golgi to vacuole transport; protein targeting to vacuole; and ubiquitin-dependent protein catabolic process. Predicted to be integral component of membrane. Predicted to be part of Golgi transport complex. Predicted to be active in endosome; membrane; and trans-Golgi network. Orthologous to human RNF215 (ring finger protein 215). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in lung adult (RPKM 27.0), ovary adult (RPKM 20.1) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    11 A1; 11 2.89 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (4085158..4091193)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (4135157..4141193)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene SEC14-like lipid binding 2 Neighboring gene predicted gene, 51934 Neighboring gene transformer 2 beta homolog pseudogene Neighboring gene microRNA 3060 Neighboring gene coiled-coil domain containing 157 Neighboring gene splicing factor 3a, subunit 1 Neighboring gene STARR-positive B cell enhancer ABC_E727 Neighboring gene TBC1 domain family, member 10a Neighboring gene STARR-positive B cell enhancer ABC_E2978 Neighboring gene cytosolic arginine sensor for mTORC1 subunit 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC106323, MGC144708, MGC144709

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RING finger protein 215

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001363143.1 → NP_001350072.1  RING finger protein 215 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AL807825
      Conserved Domains (1) summary
      cd16670
      Location:298 → 347
      RING-H2_RNF215; RING finger, H2 subclass, found in RING finger protein 215 (RNF215) and similar proteins

    2. NM_027859.3 → NP_082135.2  RING finger protein 215 isoform 1 precursor

      See identical proteins and their annotated locations for NP_082135.2

      Status: VALIDATED

      Source sequence(s)
      BC115907, BM120893, BM948157, CX203997
      Consensus CDS
      CCDS24378.1
      UniProtKB/Swiss-Prot
      Q5SPX2, Q5SPX3, Q5SPX4, Q9DCW1
      Related
      ENSMUSP00000003677.5, ENSMUST00000003677.11
      Conserved Domains (1) summary
      pfam13639
      Location:325 → 368
      zf-RING_2; Ring finger domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      4085158..4091193
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_003949509.2 RNA Sequence

    2. XR_380981.4 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5SPX3.1 GenPept UniProtKB/Swiss-Prot:Q5SPX3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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