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    Rv3557c HTH-type transcriptional regulator KstR2 [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 887467, updated on 6-Oct-2023

    Summary

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    Gene symbol
    Rv3557c
    Gene description
    HTH-type transcriptional regulator KstR2
    Locus tag
    Rv3557c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (3997029..3997631, complement)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene acetyl-CoA acetyltransferase FadA Neighboring gene PPE family protein PPE64 Neighboring gene oxidoreductase Neighboring gene acyl-CoA dehydrogenase FadE30

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural and functional characterization of a ketosteroid transcriptional regulator of Mycobacterium tuberculosis. Crowe AM, et al. J Biol Chem, 2015 Jan 9. PMID 25406313, Free PMC Article
    2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The results provide insight into KstR2-mediated regulation of expression of steroid catabolic genes and the determinants of ligand binding in TetR family repressors.
      Title: Structural and functional characterization of a ketosteroid transcriptional regulator of Mycobacterium tuberculosis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    HTH-type transcriptional regulator KstR2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      3997029..3997631 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_218074.1 HTH-type transcriptional regulator KstR2 [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_218074.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2I7WCX0
      Conserved Domains (2) summary
      pfam00440
      Location:15 → 61
      TetR_N; Bacterial regulatory proteins, tetR family
      pfam17932
      Location:80 → 195
      TetR_C_24; Tetracyclin repressor-like, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P9WMB9.1

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