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    Fam186a family with sequence similarity 186, member A [ Mus musculus (house mouse) ]

    Gene ID: 72277, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Fam186aprovided by MGI
    Official Full Name
    family with sequence similarity 186, member Aprovided by MGI
    Primary source
    MGI:MGI:2685766
    See related
    Ensembl:ENSMUSG00000045350 AllianceGenome:MGI:2685766
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm920; 1700030F18Rik
    Summary
    Orthologous to human FAM186A (family with sequence similarity 186 member A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 20.8) See more
    Orthologs
    human all
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    Genomic context

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    See Fam186a in Genome Data Viewer
    Location:
    15 F1; 15 56.13 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (99816226..99864974, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (99918345..99967093, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700121M21 gene Neighboring gene ubiquinol-cytochrome c reductase hinge protein, pseudogene 1 Neighboring gene ribosomal protein S10 pseudogene Neighboring gene predicted gene, 21917 Neighboring gene RIKEN cDNA 2310068J16 gene Neighboring gene STARR-positive B cell enhancer ABC_E3157 Neighboring gene La ribonucleoprotein 4 Neighboring gene STARR-seq mESC enhancer starr_39735 Neighboring gene STARR-positive B cell enhancer mm9_chr15:99890852-99891153 Neighboring gene disco interacting protein 2 homolog B Neighboring gene STARR-seq mESC enhancer starr_39737

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM186A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028180.3 → NP_082456.1  protein FAM186A

      See identical proteins and their annotated locations for NP_082456.1

      Status: VALIDATED

      Source sequence(s)
      AC138177, AK006542
      Consensus CDS
      CCDS37207.1
      UniProtKB/Swiss-Prot
      Q9D9R9
      Related
      ENSMUSP00000053434.9, ENSMUST00000062631.15

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      99816226..99864974 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030248785.1 → XP_030104645.1  protein FAM186A isoform X2

      UniProtKB/TrEMBL
      K3W4Q5
      Related
      ENSMUSP00000097783.5, ENSMUST00000100209.6
      Conserved Domains (2) summary
      PHA03247
      Location:1228 → 1632
      PHA03247; large tegument protein UL36; Provisional
      COG5043
      Location:25 → 255
      MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]

    2. XM_036159601.1 → XP_036015494.1  protein FAM186A isoform X3

      UniProtKB/TrEMBL
      K3W4Q5
      Conserved Domains (2) summary
      PHA03247
      Location:1155 → 1594
      PHA03247; large tegument protein UL36; Provisional
      COG5043
      Location:25 → 255
      MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]

    3. XM_036159600.1 → XP_036015493.1  protein FAM186A isoform X1

      UniProtKB/TrEMBL
      K3W4Q5
      Conserved Domains (2) summary
      PHA03247
      Location:1228 → 1632
      PHA03247; large tegument protein UL36; Provisional
      COG5043
      Location:25 → 255
      MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]

    4. XM_036159602.1 → XP_036015495.1  protein FAM186A isoform X4

      UniProtKB/TrEMBL
      K3W4Q5
      Conserved Domains (1) summary
      PHA03247
      Location:1079 → 1483
      PHA03247; large tegument protein UL36; Provisional

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001162867.1: Suppressed sequence

      Description
      NM_001162867.1: This RefSeq was temporarily suppressed because the CDS was partial.

    2. NM_001195694.1: Suppressed sequence

      Description
      NM_001195694.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D9R9.2 GenPept UniProtKB/Swiss-Prot:Q9D9R9

    Gene LinkOut

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