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    OEP80 outer envelope protein of 80 kDa [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832082, updated on 3-Apr-2024

    Summary

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    Gene symbol
    OEP80
    Gene description
    outer envelope protein of 80 kDa
    Primary source
    Araport:AT5G19620
    Locus tag
    AT5G19620
    See related
    TAIR:AT5G19620
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA OUTER ENVELOPE PROTEIN OF 80 KDA; ATOEP80; EMB213; EMBRYO DEFECTIVE 213; outer envelope protein of 80 kDa; T29J13.40; T29J13_40; TOC75; TOC75-V; translocon at the outer envelope membrane of chloroplasts 75-V
    Summary
    AtOEP80 is paralog to the chloroplastic protein translocation channel Toc75. Mutations in this locus result in embryo lethality.
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    Genomic context

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    See OEP80 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    16
    Sequence:
    Chromosome: 5; NC_003076.8 (6623197..6627894)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene GNOM-like 2 Neighboring gene miscRNA Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Insertion of plastidic β-barrel proteins into the outer envelopes of plastids involves an intermembrane space intermediate formed with Toc75-V/OEP80. Gross LE, et al. Plant Cell, 2021 Jul 2. PMID 33624803, Free PMC Article
    2. Multi-functional roles for the polypeptide transport associated domains of Toc75 in chloroplast protein import. Paila YD, et al. Elife, 2016 Mar 21. PMID 26999824, Free PMC Article
    3. The Omp85-related chloroplast outer envelope protein OEP80 is essential for viability in Arabidopsis. Patel R, et al. Plant Physiol, 2008 Sep. PMID 18621981, Free PMC Article
    4. The chloroplastic protein translocation channel Toc75 and its paralog OEP80 represent two distinct protein families and are targeted to the chloroplastic outer envelope by different mechanisms. Inoue K, et al. Plant J, 2004 Aug. PMID 15255865
    5. In vivo analyses of the roles of essential Omp85-related proteins in the chloroplast outer envelope membrane. Huang W, et al. Plant Physiol, 2011 Sep. PMID 21757633, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CRUMPLED LEAF supports plastid OUTER ENVELOPE PROTEIN OF 80 KDA complex formation in Arabidopsis.
      Title: CRUMPLED LEAF supports plastid OUTER ENVELOPE PROTEIN OF 80 KDA complex formation in Arabidopsis.
    2. Insertion of plastidic beta-barrel proteins into the outer envelopes of plastids involves an intermembrane space intermediate formed with Toc75-V/OEP80.
      Title: Insertion of plastidic β-barrel proteins into the outer envelopes of plastids involves an intermembrane space intermediate formed with Toc75-V/OEP80.
    3. The authors demonstrate that the Toc75 POTRA domains are essential for protein import and contribute to interactions with TOC receptors, thereby coupling preprotein recognition at the chloroplast surface with membrane translocation.
      Title: Multi-functional roles for the polypeptide transport associated domains of Toc75 in chloroplast protein import.
    4. Data indicate that OEP80-T7(atToc75-V) and atToc75-III showed distinct migration patterns on blue native-PAGE.
      Title: OEP80, an essential protein paralogous to the chloroplast protein translocation channel Toc75, exists as a 70-kD protein in the Arabidopsis thaliana chloroplast outer envelope.
    5. Heterozygotes of mutants produced approximately 25% aborted seeds upon self-pollination. The N-terminal region is not essential for the targeting, biogenesis, or functionality of the protein.
      Title: The Omp85-related chloroplast outer envelope protein OEP80 is essential for viability in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_121967.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    outer envelope protein of 80 kDa
    NP_568378.1
    • outer envelope protein of 80 kDa (OEP80); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: mitochondrion, chloroplast, plastid, membrane, chloroplast envelope; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Bacterial surface antigen (D15) (InterPro:IPR000184), Surface antigen variable number (InterPro:IPR010827); BEST Arabidopsis thaliana protein match is: Outer membrane OMP85 family protein (TAIR:AT3G44160.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      6623197..6627894
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121967.4 → NP_568378.1  outer envelope protein of 80 kDa [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568378.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C5J8
      UniProtKB/TrEMBL
      A0A178UCU2, A0A5S9Y5K8, A0A7G2F8T3
      Conserved Domains (1) summary
      pfam01103
      Location:429 → 731
      Bac_surface_Ag; Surface antigen
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C5J8.1

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