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    Golga7 golgin A7 [ Mus musculus (house mouse) ]

    Gene ID: 57437, updated on 21-Apr-2024

    Summary

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    Official Symbol
    Golga7provided by MGI
    Official Full Name
    golgin A7provided by MGI
    Primary source
    MGI:MGI:1931029
    See related
    Ensembl:ENSMUSG00000015341 AllianceGenome:MGI:1931029
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    GCP16; HSPC041; GOLGA3AP1; C130038N16Rik
    Summary
    Predicted to be involved in establishment of protein localization to membrane; peptidyl-L-cysteine S-palmitoylation; and protein stabilization. Predicted to act upstream of or within Golgi to plasma membrane transport. Predicted to be located in Golgi membrane. Predicted to be intrinsic component of Golgi membrane. Predicted to be part of palmitoyltransferase complex. Predicted to be active in Golgi stack. Is expressed in several structures, including alimentary system; eye; genitourinary system; integumental system; and nervous system. Orthologous to human GOLGA7 (golgin A7). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E14 (RPKM 35.4), limb E14.5 (RPKM 33.1) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    8 A2; 8 11.42 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (23731342..23747096, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (23241326..23258903, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30247 Neighboring gene glycerol-3-phosphate acyltransferase 4 Neighboring gene STARR-positive B cell enhancer ABC_E10494 Neighboring gene STARR-positive B cell enhancer ABC_E356 Neighboring gene GINS complex subunit 4 Neighboring gene predicted gene, 39141 Neighboring gene predicted gene, 24335 Neighboring gene predicted gene, 53407

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras. Wang T, et al. Cell, 2017 Feb 23. PMID 28162770, Free PMC Article
    2. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 
    • Endonuclease-mediated (1) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC30271, MGC102434, MGC118465

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in Golgi to plasma membrane protein transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within Golgi to plasma membrane transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in peptidyl-L-cysteine S-palmitoylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in peptidyl-L-cysteine S-palmitoylation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein stabilization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in Golgi stack IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi stack ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of palmitoyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of palmitoyltransferase complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    golgin subfamily A member 7
    Names
    golgi autoantigen, golgin subfamily a, 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042484.1 → NP_001035949.1  golgin subfamily A member 7

      See identical proteins and their annotated locations for NP_001035949.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC126038, AK150696, BY330336
      Consensus CDS
      CCDS40297.1
      UniProtKB/Swiss-Prot
      Q8BN18, Q91W53, Q9JJE0
      Related
      ENSMUSP00000062983.7, ENSMUST00000051094.9
      Conserved Domains (1) summary
      pfam10256
      Location:12 → 124
      Erf4; Golgin subfamily A member 7/ERF4 family

    2. NM_020585.2 → NP_065610.2  golgin subfamily A member 7

      See identical proteins and their annotated locations for NP_065610.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC126038, AK150696, BY330336
      Consensus CDS
      CCDS40297.1
      UniProtKB/Swiss-Prot
      Q8BN18, Q91W53, Q9JJE0
      Related
      ENSMUSP00000112935.2, ENSMUST00000121783.7
      Conserved Domains (1) summary
      pfam10256
      Location:12 → 124
      Erf4; Golgin subfamily A member 7/ERF4 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      23731342..23747096 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006509179.5 → XP_006509242.1  golgin subfamily A member 7 isoform X1

      See identical proteins and their annotated locations for XP_006509242.1

      Conserved Domains (1) summary
      pfam10256
      Location:12 → 123
      Erf4; Golgin subfamily A member 7/ERF4 family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q91W53.1 GenPept UniProtKB/Swiss-Prot:Q91W53

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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