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    2810021J22Rik RIKEN cDNA 2810021J22 gene [ Mus musculus (house mouse) ]

    Gene ID: 69944, updated on 8-Feb-2024

    Summary

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    Official Symbol
    2810021J22Rikprovided by MGI
    Official Full Name
    RIKEN cDNA 2810021J22 geneprovided by MGI
    Primary source
    MGI:MGI:1917194
    See related
    Ensembl:ENSMUSG00000020491 AllianceGenome:MGI:1917194
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in early conceptus; inner cell mass; and oocyte. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in thymus adult (RPKM 4.1), CNS E11.5 (RPKM 2.3) and 26 other tissues See more
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    Genomic context

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    Location:
    11 B1.3; 11 36.34 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (58751310..58775164)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (58860484..58884529)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily AF member 1 Neighboring gene STARR-positive B cell enhancer ABC_E588 Neighboring gene olfactory receptor family 9 subfamily E member 1 Neighboring gene predicted gene 12258 Neighboring gene STARR-positive B cell enhancer ABC_E9824 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:58697199-58697308 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:58697335-58697545 Neighboring gene zinc finger protein 39 Neighboring gene STARR-positive B cell enhancer ABC_E2990 Neighboring gene predicted gene 12257

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation. Alvarez-Dominguez JR, et al. Blood, 2014 Jan 23. PMID 24200680, Free PMC Article
    2. Widespread and dynamic translational control of red blood cell development. Alvarez-Dominguez JR, et al. Blood, 2017 Feb 2. PMID 27899360, Free PMC Article
    3. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
    4. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    5. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC69944

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172403.2 → NP_765991.1  uncharacterized protein LOC69944

      See identical proteins and their annotated locations for NP_765991.1

      Status: PREDICTED

      Source sequence(s)
      BC058081
      Consensus CDS
      CCDS24751.1
      UniProtKB/TrEMBL
      Q8BIB6
      Related
      ENSMUSP00000073579.4, ENSMUST00000073924.10
      Conserved Domains (4) summary
      smart00349
      Location:8 → 67
      KRAB; krueppel associated box
      COG5048
      Location:396 → 539
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:456 → 476
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:370 → 392
      zf-C2H2; Zinc finger, C2H2 type

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      58751310..58775164
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030246292.1 → XP_030102152.1  uncharacterized protein LOC69944 isoform X1

      UniProtKB/TrEMBL
      Q8BIB6
      Conserved Domains (4) summary
      smart00349
      Location:8 → 67
      KRAB; krueppel associated box
      COG5048
      Location:396 → 539
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:456 → 476
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:370 → 392
      zf-C2H2; Zinc finger, C2H2 type

    2. XM_030246294.2 → XP_030102154.1  uncharacterized protein LOC69944 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:314 → 457
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:374 → 394
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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