Sycn syncollin [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Sycnprovided by MGI
Official Full Name: syncollinprovided by MGI
Primary source: MGI:MGI:1915666
See related: Ensembl:ENSMUSG00000084174 AllianceGenome:MGI:1915666
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: SYL; 0910001K16Rik; 1810038B08Rik
Summary: Predicted to be involved in exocytosis. Predicted to be located in cytoplasmic vesicle and membrane. Predicted to be active in secretory granule membrane. Orthologous to human SYCN (syncollin). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in small intestine adult (RPKM 2845.3), colon adult (RPKM 1929.8) and 2 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 A3; 7 16.83 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (28240310..28241635)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (28540885..28542210)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

syncollin is required for efficient exocytosis in the pancreatic acinar cell, and it plays a particularly important role in compound exocytosis
Title: Syncollin is required for efficient zymogen granule exocytosis.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1) 1 citation

General gene information

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Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
acts_upstream_of_or_within exocytosis	IEA Inferred from Electronic Annotation more info
involved_in exocytosis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in secretory granule membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: syncollin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.