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    Vegp2 von Ebners gland protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 94106, updated on 9-May-2024

    Summary

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    Symbol
    Vegp2provided by RGD
    Full Name
    von Ebners gland protein 2provided by RGD
    Primary source
    RGD:620384
    See related
    Ensembl:ENSRNOG00000033761 AllianceGenome:RGD:620384
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable chloride ion binding activity; signaling receptor binding activity; and zinc ion binding activity. Predicted to be involved in retina homeostasis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to several human genes including LCN1 (lipocalin 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Testes (RPKM 5.8), Thymus (RPKM 1.8) and 1 other tissue See more
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    Genomic context

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    See Vegp2 in Genome Data Viewer
    Location:
    3p13
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (29914540..29940231, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (9516457..9542088, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (4217260..4221330, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102547612 Neighboring gene ring finger protein 138, pseudogene 3 Neighboring gene activated RNA polymerase II transcriptional coactivator p15 pseudogene Neighboring gene lipocalin 1 Neighboring gene vomeronasal secretory protein 2-like Neighboring gene ribosomal protein L9, pseudogene 31

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Structural organization of the genes for rat von Ebner's gland proteins 1 and 2 reveals their close relationship to lipocalins. Kock K, et al. Eur J Biochem, 1994 May 1. PMID 7514123
    2. Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy. Pieragostino D, et al. Mol Biosyst, 2013 Jun. PMID 23580065
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables small molecule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in sensory perception of taste IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    von Ebner gland protein 2
    Names
    VEG protein 2
    von Ebner gland protein 2-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001430153.1 → NP_001417082.1  von Ebner gland protein 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003

    2. NM_053574.2 → NP_446026.1  von Ebner gland protein 2 isoform 1 precursor

      See identical proteins and their annotated locations for NP_446026.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/Swiss-Prot
      P41244
      UniProtKB/TrEMBL
      R9PXY4
      Related
      ENSRNOP00000041023.4, ENSRNOT00000042910.5
      Conserved Domains (1) summary
      cd19414
      Location:26 → 173
      lipocalin_1_3_4_13-like; lipocalin-1, -3, -4, -13 and similar proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      29914540..29940231 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039106004.2 → XP_038961932.1  von Ebner gland protein 2 isoform X2

      Conserved Domains (1) summary
      cd19414
      Location:1 → 116
      lipocalin_1_3_4_13-like; lipocalin-1, -3, -4, -13 and similar proteins

    2. XM_039106003.2 → XP_038961931.1  von Ebner gland protein 2 isoform X1

      UniProtKB/TrEMBL
      A6JTH3
      Conserved Domains (1) summary
      cd19414
      Location:7 → 150
      lipocalin_1_3_4_13-like; lipocalin-1, -3, -4, -13 and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P41244.1 GenPept UniProtKB/Swiss-Prot:P41244

    Gene LinkOut

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