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    Pdxkl1 pyridoxal kinase like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361819, updated on 2-May-2024

    Summary

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    Official Symbol
    Pdxkl1provided by RGD
    Official Full Name
    pyridoxal kinase like 1provided by RGD
    Primary source
    RGD:1566085
    See related
    Ensembl:ENSRNOG00000068407 AllianceGenome:RGD:1566085
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1566085
    Summary
    Predicted to be involved in phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 265.4), Liver (RPKM 55.7) and 7 other tissues See more
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    Genomic context

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    See Pdxkl1 in Genome Data Viewer
    Location:
    20p12
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (10162634..10192271, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (10162934..10192572, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (10883952..10912870, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene heat shock transcription factor 2 binding protein Neighboring gene ribosomal RNA processing 1B Neighboring gene pyridoxal kinase Neighboring gene uncharacterized LOC134483884 Neighboring gene cystatin B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables pyridoxal kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in pyridoxal 5'-phosphate salvage IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    similar to pyridoxal (pyridoxine, vitamin B6) kinase
    Names
    pyridoxal kinase
    pyridoxal kinase-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001402486.1 → NP_001389415.1  similar to pyridoxal (pyridoxine, vitamin B6) kinase

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020
      UniProtKB/TrEMBL
      A0A8I6AAM1
      Related
      ENSRNOP00000090354.1, ENSRNOT00000098080.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      10162634..10192271 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039099174.2 → XP_038955102.1  similar to pyridoxal (pyridoxine, vitamin B6) kinase isoform X1

      Conserved Domains (1) summary
      cl00192
      Location:1 → 212
      ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...

    2. XM_039099175.2 → XP_038955103.1  similar to pyridoxal (pyridoxine, vitamin B6) kinase isoform X2

      Conserved Domains (1) summary
      cl00192
      Location:1 → 189
      ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...

    3. XM_063279232.1 → XP_063135302.1  similar to pyridoxal (pyridoxine, vitamin B6) kinase isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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