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    Prb1 proline-rich protein BstNI subfamily 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 257652, updated on 2-May-2024

    Summary

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    Official Symbol
    Prb1provided by RGD
    Official Full Name
    proline-rich protein BstNI subfamily 1provided by RGD
    Primary source
    RGD:628796
    See related
    Ensembl:ENSRNOG00000010449 AllianceGenome:RGD:628796
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Prpg1
    Summary
    Predicted to be located in extracellular region. Orthologous to human PRB1 (proline rich protein BstNI subfamily 1); PRB3 (proline rich protein BstNI subfamily 3); and PRB4 (proline rich protein BstNI subfamily 4). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Prb1 in Genome Data Viewer
    Location:
    4q42
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (167240337..167243803, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (165508927..165512393, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (165985029..165988466, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene taste receptor, type 2, member 114 Neighboring gene nuclear distribution C, dynein complex regulator, pseudogene 1 Neighboring gene proline-rich protein MP5 Neighboring gene proline-rich protein BstNI subfamily 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Nucleotide sequence analysis of a proline-rich protein cDNA and peptide homologies of rat and human proline-rich proteins. Ziemer MA, et al. J Biol Chem, 1984 Aug 25. PMID 6547951
    2. Novel secretory proline-rich proteoglycans from rat parotid. Cloning and characterization by expression in AtT-20 cells. Castle AM, et al. J Biol Chem, 1993 Sep 25. PMID 8376404
    3. Novel multigene families encoding highly repetitive peptide sequences. Sequence analyses of rat and mouse proline-rich protein cDNAs. Clements S, et al. J Biol Chem, 1985 Nov 5. PMID 3840480

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    acidic proline-rich protein PRP33
    Names
    proline-rich proteoglycan 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395623.1 → NP_001382552.1  acidic proline-rich protein PRP33 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A6IMA3
      Related
      ENSRNOP00000013885.6, ENSRNOT00000013887.6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      167240337..167243803 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_172064.1: Suppressed sequence

      Description
      NM_172064.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P04474.1 GenPept UniProtKB/Swiss-Prot:P04474

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.