Poln DNA polymerase nu [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Polnprovided by RGD
Official Full Name: DNA polymerase nuprovided by RGD
Primary source: RGD:7675413
See related: Ensembl:ENSRNOG00000069005 AllianceGenome:RGD:7675413
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable DNA-directed DNA polymerase activity and cyclin binding activity. Predicted to be involved in double-strand break repair via homologous recombination; interstrand cross-link repair; and translesion synthesis. Predicted to be located in nucleoplasm. Orthologous to human POLN (DNA polymerase nu). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information: not in current annotation release
Expression: Biased expression in Testes (RPKM 50.5), Brain (RPKM 20.9) and 6 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 14q21

Annotation release	Status	Assembly	Chr	Location
RS_2023_06	latest, but not current	mRatBN7.2 (GCF_015227675.2)	14	NC_051349.1 (76579983..76752460)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	14	NC_005113.4 (81837764..82037999)

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-directed DNA polymerase activity	IBA Inferred from Biological aspect of Ancestor more info
enables DNA-directed DNA polymerase activity	ISO Inferred from Sequence Orthology more info
enables cyclin binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in DNA-templated DNA replication	IEA Inferred from Electronic Annotation more info
involved_in cell division	IEA Inferred from Electronic Annotation more info
involved_in double-strand break repair	IBA Inferred from Biological aspect of Ancestor more info
involved_in double-strand break repair via homologous recombination	ISO Inferred from Sequence Orthology more info
involved_in interstrand cross-link repair	ISO Inferred from Sequence Orthology more info
involved_in translesion synthesis	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
NOT located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: DNA polymerase nu

Names: DNA polymerase N; polymerase (DNA directed) nu; polymerase (DNA) nu

NP_001415859.1

EC 2.7.7.7

NP_001415860.1

EC 2.7.7.7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001428930.1 → NP_001415859.1 DNA polymerase nu

Status: VALIDATED

Source sequence(s)

JAXUCZ010000014
NM_001428931.1 → NP_001415860.1 DNA polymerase nu

Status: VALIDATED

Source sequence(s)

JAXUCZ010000014