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    Pum1 pumilio RNA-binding family member 1 [ Mus musculus (house mouse) ]

    Gene ID: 80912, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Pum1provided by MGI
    Official Full Name
    pumilio RNA-binding family member 1provided by MGI
    Primary source
    MGI:MGI:1931749
    See related
    Ensembl:ENSMUSG00000028580 AllianceGenome:MGI:1931749
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pumm; mKIAA0099
    Summary
    Enables mRNA 3'-UTR binding activity. Involved in several processes, including adult locomotory behavior; posttranscriptional regulation of gene expression; and spermatogenesis. Acts upstream of or within posttranscriptional regulation of gene expression. Located in cytoplasm. Is expressed in several structures, including central nervous system; intestine; olfactory epithelium; retina; and testis. Human ortholog(s) of this gene implicated in cerebellar ataxia type 47. Orthologous to human PUM1 (pumilio RNA binding family member 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in ovary adult (RPKM 32.2), whole brain E14.5 (RPKM 27.8) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    4 D2.2; 4 63.43 cM
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (130390509..130508875)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (130663238..130781564)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene Na+/K+ transporting ATPase interacting 1 Neighboring gene STARR-seq mESC enhancer starr_11526 Neighboring gene STARR-seq mESC enhancer starr_11530 Neighboring gene predicted gene, 53228 Neighboring gene STARR-seq mESC enhancer starr_11531 Neighboring gene STARR-seq mESC enhancer starr_11533 Neighboring gene small nucleolar RNA, C/D box 85 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:130330830-130331017 Neighboring gene predicted gene, 24091 Neighboring gene STARR-positive B cell enhancer ABC_E6227 Neighboring gene predicted gene, 23711 Neighboring gene predicted gene 12972 Neighboring gene syndecan 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Dosage sensitivity to Pumilio1 variants in the mouse brain reflects distinct molecular mechanisms. Botta S, et al. EMBO J, 2023 Jun 1. PMID 37070548, Free PMC Article
    2. A role of Pumilio 1 in mammalian oocyte maturation and maternal phase of embryogenesis. Mak W, et al. Cell Biosci, 2018. PMID 30364263, Free PMC Article
    3. Loss of preimplantation embryo resulting from a Pum1 gene trap mutation. Zhang C, et al. Biochem Biophys Res Commun, 2015 Jun 19. PMID 25896760
    4. PUMILIO proteins promote colorectal cancer growth via suppressing p21. Gong Y, et al. Nat Commun, 2022 Mar 25. PMID 35338151, Free PMC Article
    5. Changes in subcellular structures and states of pumilio 1 regulate the translation of target Mad2 and cyclin B1 mRNAs. Takei N, et al. J Cell Sci, 2020 Dec 11. PMID 33148609

    See all (60) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Dosage sensitivity to Pumilio1 variants in the mouse brain reflects distinct molecular mechanisms.
      Title: Dosage sensitivity to Pumilio1 variants in the mouse brain reflects distinct molecular mechanisms.
    2. Sertoli cell PUMILIO proteins modulate mouse testis size through translational control of cell cycle regulators.
      Title: Sertoli cell PUMILIO proteins modulate mouse testis size through translational control of cell cycle regulators.
    3. Changes in subcellular structures and states of pumilio 1 regulate the translation of target Mad2 and cyclin B1 mRNAs.
      Title: Changes in subcellular structures and states of pumilio 1 regulate the translation of target Mad2 and cyclin B1 mRNAs.
    4. Pum1 and Pum2 achieve these two complementary aspects of pluripotency by forming a negative interregulatory feedback loop that directly regulates at least 1,486 mRNAs. Pum1 and Pum2 regulate target mRNAs not only by repressing translation, but also by promoting translation and enhancing or reducing mRNA stability of different target mRNAs.
      Title: Pumilio proteins utilize distinct regulatory mechanisms to achieve complementary functions required for pluripotency and embryogenesis.
    5. Pum1 and Pum2 regulate mouse body and organ size by post-transcriptional repression of the cell cycle inhibitor Cdkn1b.
      Title: Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b.
    6. major role of Pum1 and Pum2 in hippocampal neurogenesis and function
      Title: Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins.
    7. important role in the establishment of the primordial follicle pool, meiosis, and female reproductive competency
      Title: An Important Role of Pumilio 1 in Regulating the Development of the Mammalian Female Germline.
    8. Data indicate a role for RNA-binding protein Pum1 in early embryonic development.
      Title: Loss of preimplantation embryo resulting from a Pum1 gene trap mutation.
    9. The RNA-binding protein PUMILIO1 (PUM1) not only directly regulates ATAXIN1 but also plays an unexpectedly important role in neuronal function. Loss of Pum1 caused progressive motor dysfunction and SCA1-like neurodegeneration with motor impairment, primarily by increasing Ataxin1 levels.
      Title: Pumilio1 haploinsufficiency leads to SCA1-like neurodegeneration by increasing wild-type Ataxin1 levels.
    10. Key components of the p53 pathway are coordinately regulated by Pumilio 1 at the posttranscriptional level, which may exemplify an RNA operon.
      Title: Pumilio 1 suppresses multiple activators of p53 to safeguard spermatogenesis.
    Submit: New GeneRIF Correction See all GeneRIFs (11)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (5)  1 citation
    • Gene trapped (3) 
    • Endonuclease-mediated (3) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables mRNA 3'-UTR binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mRNA 3'-UTR binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables mRNA 3'-UTR binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables miRNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in adult locomotory behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA destabilization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in miRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in miRNA processing ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of RIG-I signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of miRNA-mediated gene silencing ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in post-transcriptional gene silencing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within post-transcriptional regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within post-transcriptional regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    acts_upstream_of_positive_effect post-transcriptional regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of cell cycle ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of chromosome segregation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of mRNA stability IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of mRNA stability ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in stem cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in P-body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in axon ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasmic stress granule ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    pumilio homolog 1
    Names
    pumilio 1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159603.2 → NP_001153075.1  pumilio homolog 1 isoform 2

      See identical proteins and their annotated locations for NP_001153075.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses multiple alternate in-frame splice sites, compared to variant 1, which results in a shorter protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      AK162742, BE653001, BU708930, BY782432, CB724122, CF157665, CF746520, CJ064695, CJ227969, CN530452, CN530471, CN538180, CN724656, CV559585
      Consensus CDS
      CCDS51311.1
      UniProtKB/TrEMBL
      Q3UR00
      Related
      ENSMUSP00000095476.3, ENSMUST00000097864.9
      Conserved Domains (1) summary
      cd07920
      Location:843 → 1164
      Pumilio; Pumilio-family RNA binding domain

    2. NM_001159604.2 → NP_001153076.1  pumilio homolog 1 isoform 3

      See identical proteins and their annotated locations for NP_001153076.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate in-frame splice site, compared to variant 1, which results in a shorter protein (isoform 3), compared to isoform 1.
      Source sequence(s)
      AK161135, AK162742, BC048174, BY782432, CF746520, CJ227969
      Consensus CDS
      CCDS51312.1
      UniProtKB/TrEMBL
      Q3TQ21, Q3UR00
      Related
      ENSMUSP00000095474.3, ENSMUST00000097862.3
      Conserved Domains (1) summary
      cd07920
      Location:843 → 1166
      Pumilio; Pumilio-family RNA binding domain

    3. NM_001159605.2 → NP_001153077.1  pumilio homolog 1 isoform 4

      See identical proteins and their annotated locations for NP_001153077.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) has multiple coding region differences, compared to variant 1, which results in a shorter protein (isoform 4), compared to isoform 1.
      Source sequence(s)
      AK161135, AK162742, BY782432, CF746520, CJ227969
      Consensus CDS
      CCDS51313.1
      UniProtKB/TrEMBL
      Q3TTW5, Q3UR00
      Related
      ENSMUSP00000101613.3, ENSMUST00000105992.9
      Conserved Domains (1) summary
      cd07920
      Location:747 → 1070
      Pumilio; Pumilio-family RNA binding domain

    4. NM_001159606.2 → NP_001153078.1  pumilio homolog 1 isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) has multiple coding region differences, compared to variant 1, which results in a shorter protein (isoform 5), compared to isoform 1.
      Source sequence(s)
      AK147185, AK161135, AK162742, BY782432, CF746520, CJ227969, CN526490
      Consensus CDS
      CCDS51314.1
      UniProtKB/TrEMBL
      E9Q6M7, Q3UHW0
      Related
      ENSMUSP00000101612.3, ENSMUST00000105991.9
      Conserved Domains (1) summary
      cd07920
      Location:601 → 922
      Pumilio; Pumilio-family RNA binding domain

    5. NM_001356564.1 → NP_001343493.1  pumilio homolog 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AK162742, AL627104, CF746520, CJ227969
      UniProtKB/TrEMBL
      Q3TRI4
      Conserved Domains (1) summary
      cd07920
      Location:765 → 1086
      Pumilio; Pumilio-family RNA binding domain

    6. NM_001356565.1 → NP_001343494.1  pumilio homolog 1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AK162742, AL627104, BY782432, CF746520, CJ227969, CN456820, CN724656, CV559585
      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:747 → 1068
      Pumilio; Pumilio-family RNA binding domain

    7. NM_001356566.1 → NP_001343495.1  pumilio homolog 1 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AK162742, AL627104, BE653001, BY782432, CF746520, CJ093090, CJ227969, CN724656, CV559585
      UniProtKB/TrEMBL
      Q3UHW0
      Conserved Domains (1) summary
      cd07920
      Location:601 → 924
      Pumilio; Pumilio-family RNA binding domain

    8. NM_030722.3 → NP_109647.2  pumilio homolog 1 isoform 1

      See identical proteins and their annotated locations for NP_109647.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AK162742, BE653001, BU708930, BY782432, CB724122, CF746520, CJ064695, CJ227969, CN530452, CN530471, CN538180, CN724656
      Consensus CDS
      CCDS18710.1
      UniProtKB/Swiss-Prot
      Q80U78, Q80X96, Q80YU8, Q8BPV7, Q9EPU6
      UniProtKB/TrEMBL
      Q3UR00
      Related
      ENSMUSP00000030315.7, ENSMUST00000030315.13
      Conserved Domains (1) summary
      cd07920
      Location:844 → 1167
      Pumilio; Pumilio-family RNA binding domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      130390509..130508875
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539291.5 → XP_006539354.1  pumilio homolog 1 isoform X1

      See identical proteins and their annotated locations for XP_006539354.1

      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:848 → 1171
      Pumilio; Pumilio-family RNA binding domain

    2. XM_006539294.5 → XP_006539357.1  pumilio homolog 1 isoform X3

      See identical proteins and their annotated locations for XP_006539357.1

      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:848 → 1169
      Pumilio; Pumilio-family RNA binding domain

    3. XM_006539296.5 → XP_006539359.1  pumilio homolog 1 isoform X10

      See identical proteins and their annotated locations for XP_006539359.1

      UniProtKB/TrEMBL
      Q3TRI4
      Conserved Domains (1) summary
      cd07920
      Location:769 → 1092
      Pumilio; Pumilio-family RNA binding domain

    4. XM_006539297.5 → XP_006539360.1  pumilio homolog 1 isoform X11

      See identical proteins and their annotated locations for XP_006539360.1

      UniProtKB/TrEMBL
      Q3TRI4
      Conserved Domains (1) summary
      cd07920
      Location:769 → 1090
      Pumilio; Pumilio-family RNA binding domain

    5. XM_017320459.3 → XP_017175948.1  pumilio homolog 1 isoform X6

      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:844 → 1165
      Pumilio; Pumilio-family RNA binding domain

    6. XM_006539295.5 → XP_006539358.1  pumilio homolog 1 isoform X8

      See identical proteins and their annotated locations for XP_006539358.1

      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:809 → 1132
      Pumilio; Pumilio-family RNA binding domain

    7. XM_030253924.2 → XP_030109784.1  pumilio homolog 1 isoform X9

      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:809 → 1130
      Pumilio; Pumilio-family RNA binding domain

    8. XM_036164565.1 → XP_036020458.1  pumilio homolog 1 isoform X21

      UniProtKB/TrEMBL
      Q3TRI4
      Conserved Domains (1) summary
      cd07920
      Location:730 → 1053
      Pumilio; Pumilio-family RNA binding domain

    9. XM_030253933.2 → XP_030109793.1  pumilio homolog 1 isoform X32

      UniProtKB/TrEMBL
      Q3TRI4
      Conserved Domains (1) summary
      cd07920
      Location:730 → 1051
      Pumilio; Pumilio-family RNA binding domain

    10. XM_006539303.5 → XP_006539366.1  pumilio homolog 1 isoform X31

      See identical proteins and their annotated locations for XP_006539366.1

      UniProtKB/TrEMBL
      Q3U4T5
      Conserved Domains (1) summary
      cd07920
      Location:659 → 982
      Pumilio; Pumilio-family RNA binding domain

    11. XM_006539293.5 → XP_006539356.1  pumilio homolog 1 isoform X2

      See identical proteins and their annotated locations for XP_006539356.1

      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:847 → 1170
      Pumilio; Pumilio-family RNA binding domain

    12. XM_030253922.2 → XP_030109782.1  pumilio homolog 1 isoform X5

      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:843 → 1166
      Pumilio; Pumilio-family RNA binding domain

    13. XM_036164562.1 → XP_036020455.1  pumilio homolog 1 isoform X15

      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:843 → 1164
      Pumilio; Pumilio-family RNA binding domain

    14. XM_030253923.2 → XP_030109783.1  pumilio homolog 1 isoform X7

      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:842 → 1165
      Pumilio; Pumilio-family RNA binding domain

    15. XM_036164564.1 → XP_036020457.1  pumilio homolog 1 isoform X17

      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:842 → 1163
      Pumilio; Pumilio-family RNA binding domain

    16. XM_006539299.5 → XP_006539362.1  pumilio homolog 1 isoform X18

      See identical proteins and their annotated locations for XP_006539362.1

      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:752 → 1075
      Pumilio; Pumilio-family RNA binding domain

    17. XM_030253931.2 → XP_030109791.1  pumilio homolog 1 isoform X28

      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:752 → 1073
      Pumilio; Pumilio-family RNA binding domain

    18. XM_030253925.2 → XP_030109785.1  pumilio homolog 1 isoform X19

      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:748 → 1071
      Pumilio; Pumilio-family RNA binding domain

    19. XM_030253926.2 → XP_030109786.1  pumilio homolog 1 isoform X20

      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:748 → 1069
      Pumilio; Pumilio-family RNA binding domain

    20. XM_036164568.1 → XP_036020461.1  pumilio homolog 1 isoform X29

      UniProtKB/TrEMBL
      Q3TRI4
      Conserved Domains (1) summary
      cd07920
      Location:669 → 992
      Pumilio; Pumilio-family RNA binding domain

    21. XM_036164569.1 → XP_036020462.1  pumilio homolog 1 isoform X30

      UniProtKB/TrEMBL
      Q3TRI4
      Conserved Domains (1) summary
      cd07920
      Location:668 → 989
      Pumilio; Pumilio-family RNA binding domain

    22. XM_030253928.2 → XP_030109788.1  pumilio homolog 1 isoform X26

      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:713 → 1036
      Pumilio; Pumilio-family RNA binding domain

    23. XM_006539308.4 → XP_006539371.1  pumilio homolog 1 isoform X36

      See identical proteins and their annotated locations for XP_006539371.1

      UniProtKB/TrEMBL
      Q3UHW0
      Conserved Domains (1) summary
      cd07920
      Location:606 → 929
      Pumilio; Pumilio-family RNA binding domain

    24. XM_036164573.1 → XP_036020466.1  pumilio homolog 1 isoform X37

      UniProtKB/TrEMBL
      Q3UHW0
      Conserved Domains (1) summary
      cd07920
      Location:606 → 927
      Pumilio; Pumilio-family RNA binding domain

    25. XM_006539309.4 → XP_006539372.1  pumilio homolog 1 isoform X38

      See identical proteins and their annotated locations for XP_006539372.1

      UniProtKB/TrEMBL
      Q3UHW0
      Conserved Domains (1) summary
      cd07920
      Location:602 → 925
      Pumilio; Pumilio-family RNA binding domain

    26. XM_006539300.5 → XP_006539363.1  pumilio homolog 1 isoform X22

      See identical proteins and their annotated locations for XP_006539363.1

      UniProtKB/TrEMBL
      Q3U4T5
      Conserved Domains (1) summary
      cd07920
      Location:728 → 1051
      Pumilio; Pumilio-family RNA binding domain

    27. XM_030253927.2 → XP_030109787.1  pumilio homolog 1 isoform X24

      UniProtKB/TrEMBL
      Q3U4T5
      Conserved Domains (1) summary
      cd07920
      Location:724 → 1047
      Pumilio; Pumilio-family RNA binding domain

    28. XM_036164567.1 → XP_036020460.1  pumilio homolog 1 isoform X27

      UniProtKB/TrEMBL
      Q3U4T5
      Conserved Domains (1) summary
      cd07920
      Location:724 → 1045
      Pumilio; Pumilio-family RNA binding domain

    29. XM_030253930.2 → XP_030109790.1  pumilio homolog 1 isoform X25

      UniProtKB/TrEMBL
      Q3U4T5
      Conserved Domains (1) summary
      cd07920
      Location:723 → 1046
      Pumilio; Pumilio-family RNA binding domain

    30. XM_036164572.1 → XP_036020465.1  pumilio homolog 1 isoform X35

      UniProtKB/TrEMBL
      Q3U4T5
      Conserved Domains (1) summary
      cd07920
      Location:644 → 967
      Pumilio; Pumilio-family RNA binding domain

    31. XM_006539301.5 → XP_006539364.1  pumilio homolog 1 isoform X23

      See identical proteins and their annotated locations for XP_006539364.1

      UniProtKB/TrEMBL
      Q3U4T5
      Conserved Domains (1) summary
      cd07920
      Location:727 → 1050
      Pumilio; Pumilio-family RNA binding domain

    32. XM_036164571.1 → XP_036020464.1  pumilio homolog 1 isoform X34

      UniProtKB/TrEMBL
      Q3U4T5
      Conserved Domains (1) summary
      cd07920
      Location:627 → 950
      Pumilio; Pumilio-family RNA binding domain

    33. XM_006539314.5 → XP_006539377.1  pumilio homolog 1 isoform X39

      See identical proteins and their annotated locations for XP_006539377.1

      UniProtKB/TrEMBL
      Q3UHW0
      Conserved Domains (1) summary
      cd07920
      Location:486 → 809
      Pumilio; Pumilio-family RNA binding domain

    34. XM_036164574.1 → XP_036020467.1  pumilio homolog 1 isoform X40

      UniProtKB/TrEMBL
      Q3UHW0
      Conserved Domains (1) summary
      cd07920
      Location:481 → 804
      Pumilio; Pumilio-family RNA binding domain

    35. XM_006539292.4 → XP_006539355.1  pumilio homolog 1 isoform X1

      See identical proteins and their annotated locations for XP_006539355.1

      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:848 → 1171
      Pumilio; Pumilio-family RNA binding domain

    36. XM_036164561.1 → XP_036020454.1  pumilio homolog 1 isoform X4

      UniProtKB/Swiss-Prot
      Q80U78, Q80X96, Q80YU8, Q8BPV7, Q9EPU6
      UniProtKB/TrEMBL
      Q3UR00
      Conserved Domains (1) summary
      cd07920
      Location:844 → 1167
      Pumilio; Pumilio-family RNA binding domain

    37. XM_017320461.3 → XP_017175950.1  pumilio homolog 1 isoform X13

      UniProtKB/TrEMBL
      Q3TRI4
      Conserved Domains (1) summary
      cd07920
      Location:764 → 1087
      Pumilio; Pumilio-family RNA binding domain

    38. XM_017320463.2 → XP_017175952.1  pumilio homolog 1 isoform X16

      UniProtKB/TrEMBL
      Q3TRI4
      Conserved Domains (1) summary
      cd07920
      Location:764 → 1085
      Pumilio; Pumilio-family RNA binding domain

    39. XM_017320460.3 → XP_017175949.1  pumilio homolog 1 isoform X12

      UniProtKB/TrEMBL
      Q3TRI4
      Conserved Domains (1) summary
      cd07920
      Location:765 → 1088
      Pumilio; Pumilio-family RNA binding domain

    40. XM_017320462.3 → XP_017175951.1  pumilio homolog 1 isoform X14

      UniProtKB/TrEMBL
      Q3TRI4
      Conserved Domains (1) summary
      cd07920
      Location:765 → 1086
      Pumilio; Pumilio-family RNA binding domain

    41. XM_036164566.1 → XP_036020459.1  pumilio homolog 1 isoform X24

      UniProtKB/TrEMBL
      Q3U4T5
      Conserved Domains (1) summary
      cd07920
      Location:724 → 1047
      Pumilio; Pumilio-family RNA binding domain

    42. XM_036164570.1 → XP_036020463.1  pumilio homolog 1 isoform X33

      UniProtKB/TrEMBL
      Q3U4T5
      Conserved Domains (1) summary
      cd07920
      Location:632 → 955
      Pumilio; Pumilio-family RNA binding domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q80U78.2 GenPept UniProtKB/Swiss-Prot:Q80U78

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