U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    lola longitudinals lacking [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 44548, updated on 27-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    lolaprovided by FlyBase
    Official Full Name
    longitudinals lackingprovided by FlyBase
    Primary source
    FLYBASE:FBgn0283521
    Locus tag
    Dmel_CG12052
    See related
    AllianceGenome:FB:FBgn0283521
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LD17006; BcDNA:RH31485; BEST:LD03274; bs06a08.y1; btb; BTB-IV; BtbIV; CG12052; CG18376; CG18378; CG18379; CG18380; CG18381; CG30012; CG30013; CG30014; Dmel\CG12052; eyeful; fus7; l(2)00642; l(2)s3697; LD03274; Lola; LOLA; NEST:bs06a08; sw59
    Summary
    Enables DNA binding activity. Involved in several processes, including larval development; neuron differentiation; and nurse cell apoptotic process. Located in cytoplasm and nucleus. Is expressed in several structures, including epithelium; extended germ band embryo; nervous system; presumptive embryonic/larval nervous system; and testis. [provided by Alliance of Genome Resources, Apr 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    47A11-47A13; 2-62 cM
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10481894..10543291, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6369399..6430796, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene pre-lola-G Neighboring gene translin Neighboring gene Peflin Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene antisense RNA:CR45135 Neighboring gene long non-coding RNA:acal Neighboring gene pipsqueak

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Alternative trans-splicing of constant and variable exons of a Drosophila axon guidance gene, lola. Horiuchi T, et al. Genes Dev, 2003 Oct 15. PMID 14522953, Free PMC Article
    2. Alternative splicing of lola generates 19 transcription factors controlling axon guidance in Drosophila. Goeke S, et al. Nat Neurosci, 2003 Sep. PMID 12897787
    3. Drosophila lola encodes a family of BTB-transcription regulators with highly variable C-terminal domains containing zinc finger motifs. Ohsako T, et al. Gene, 2003 Jun 5. PMID 12853139
    4. cGMP-Dependent Protein Kinase Encoded by foraging Regulates Motor Axon Guidance in Drosophila by Suppressing Lola Function. Peng Q, et al. J Neurosci, 2016 Apr 20. PMID 27098704, Free PMC Article
    5. A conserved intronic U1 snRNP-binding sequence promotes trans-splicing in Drosophila. Gao JL, et al. Genes Dev, 2015 Apr 1. PMID 25838544, Free PMC Article

    See all (297) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Lola regulates Drosophila adult midgut homeostasis via non-canonical hippo signaling.
      Title: Lola regulates Drosophila adult midgut homeostasis via non-canonical hippo signaling.
    2. female-specific Lola29F is a truncation product of male-enriched Lola29M; Lola29F feminizes sex-specific neurites
      Title: Partial proteasomal degradation of Lola triggers the male-to-female switch of a dimorphic courtship circuit.
    3. In developing axons, lola cell trafficking is regulated by cGMP-dependent protein kinase.
      Title: cGMP-Dependent Protein Kinase Encoded by foraging Regulates Motor Axon Guidance in Drosophila by Suppressing Lola Function.
    4. Mid and Lola are required for somatic gonadal precursor cell cluster fusion, germ cell ensheathment, and gonad compaction in the developing Drosophila gonads.
      Title: Transcriptional regulation of Drosophila gonad formation.
    5. Loss of Lola Causes Brain Tumors.
      Title: Dedifferentiation of neurons precedes tumor formation in Lola mutants.
    6. Different lola isoforms, each having unique C-termini and zinc finger domains, may control different aspects of proliferation and differentiation in the male germline and somatic cyst stem cell lineages.
      Title: The transcriptional regulator lola is required for stem cell maintenance and germ cell differentiation in the Drosophila testis.
    7. Lola suppresses expression of the actin nucleation factor Spire, and this is crucial for its ability to promote growth of motor axons in vivo.
      Title: A genome-wide analysis reveals that the Drosophila transcription factor Lola promotes axon growth in part by suppressing expression of the actin nucleation factor Spire.
    8. alternatively spliced isoforms control self-renewal in neuroblast lineages
      Title: Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi.
    9. We propose that Lola functions as a general transcription factor that regulates the expression of multiple genes ultimately controlling PN identity and wiring specificity.
      Title: Lola regulates Drosophila olfactory projection neuron identity and targeting specificity.
    10. Lola antagonizes Notch-dependent gene expression and Notch-dependent fate transformation. Expression analysis shows that Lola is constitutively present in all photoreceptors and cone cells
      Title: Lola regulates cell fate by antagonizing Notch induction in the Drosophila eye.
    Submit: New GeneRIF Correction See all GeneRIFs (14)

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in R3/R4 cell fate commitment IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in R7 cell development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in axon guidance IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in axon midline choice point recognition IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in axon midline choice point recognition IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in dendrite morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in gonad development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in larval lymph gland hemopoiesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in larval somatic muscle development IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in larval somatic muscle development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nurse cell apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria HMP PubMed 
    involved_in positive regulation of peptidoglycan recognition protein signaling pathway HMP PubMed 
    involved_in regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleoplasm HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    longitudinals lacking
    Names
    BTB-protein-IV
    CG12052-PA
    CG12052-PAA
    CG12052-PB
    CG12052-PC
    CG12052-PD
    CG12052-PE
    CG12052-PF
    CG12052-PG
    CG12052-PH
    CG12052-PI
    CG12052-PJ
    CG12052-PK
    CG12052-PL
    CG12052-PM
    CG12052-PO
    CG12052-PP
    CG12052-PQ
    CG12052-PR
    CG12052-PT
    CG12052-PU
    CG12052-PV
    CG12052-PW
    CG12052-PX
    CG12052-PY
    CG12052-PZ
    SGP cluster fusion defects 7
    bumper-to-bumper
    e
    eyeful
    lola
    lola-PA
    lola-PAA
    lola-PB
    lola-PC
    lola-PD
    lola-PE
    lola-PF
    lola-PG
    lola-PH
    lola-PI
    lola-PJ
    lola-PK
    lola-PL
    lola-PM
    lola-PO
    lola-PP
    lola-PQ
    lola-PR
    lola-PT
    lola-PU
    lola-PV
    lola-PW
    lola-PX
    lola-PY
    lola-PZ
    longitudinal lacking
    longitudinals absent
    longitudinals-lacking
    misguided

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      10481894..10543291 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080027.6 → NP_524766.2  longitudinals lacking, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524766.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42283, Q54A11, Q9V5M2
      Conserved Domains (4) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:793 → 813
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain
      pfam13909
      Location:821 → 844
      zf-H2C2_5; C2H2-type zinc-finger domain

    2. NM_176132.4 → NP_788312.2  longitudinals lacking, isoform R [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788312.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42283, Q54A11, Q9V5M2
      Conserved Domains (4) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:793 → 813
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain
      pfam13909
      Location:821 → 844
      zf-H2C2_5; C2H2-type zinc-finger domain

    3. NM_206083.4 → NP_995805.1  longitudinals lacking, isoform X [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995805.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V5M3
      Conserved Domains (3) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain
      pfam13909
      Location:576 → 598
      zf-H2C2_5; C2H2-type zinc-finger domain

    4. NM_206082.4 → NP_995804.1  longitudinals lacking, isoform Y [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995804.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V5M3
      Conserved Domains (4) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:466 → 484
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain
      pfam13894
      Location:493 → 515
      zf-C2H2_4; C2H2-type zinc finger

    5. NM_206084.4 → NP_995806.1  longitudinals lacking, isoform W [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995806.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7KQY7, Q7KQY8, Q867I9, Q867J2, Q867U5, Q867Y0, Q86BC4, Q9V5M3
      Conserved Domains (4) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:711 → 727
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain
      pfam13909
      Location:738 → 761
      zf-H2C2_5; C2H2-type zinc-finger domain

    6. NM_176129.5 → NP_788309.2  longitudinals lacking, isoform O [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788309.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V5M3
      Related
      FBpp0088395
      Conserved Domains (4) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:532 → 552
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain
      pfam12171
      Location:532 → 560
      zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

    7. NM_176130.5 → NP_788310.2  longitudinals lacking, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788310.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V5M6
      Related
      FBpp0088394
      Conserved Domains (4) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:705 → 725
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:732 → 754
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain

    8. NM_176131.5 → NP_788311.2  longitudinals lacking, isoform P [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788311.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q058V9, Q4AB07, Q867J5, Q867M8, Q867P1, Q867T8, Q86BC2, Q8MKX4, Q9V5M5, Q9V5M6
      Related
      FBpp0088389
      Conserved Domains (3) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:851 → 871
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain

    9. NM_170617.5 → NP_724945.1  longitudinals lacking, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724945.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42284
      Related
      FBpp0088380
      Conserved Domains (2) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain

    10. NM_170618.5 → NP_724946.1  longitudinals lacking, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724946.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4UZC4, Q0E9C9, Q7KQZ4, Q867I7, Q867S0, Q867S9, Q8MKX5, Q95TS0
      Related
      FBpp0088379
      Conserved Domains (3) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00019
      Location:687 → 707
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain

    11. NM_170619.3 → NP_724949.2  longitudinals lacking, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724949.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4UZC4, Q0E9C9, Q7KQZ4, Q867I7, Q867S0, Q867S9, Q8MKX5, Q95TS0
      Conserved Domains (3) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00019
      Location:687 → 707
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain

    12. NM_176128.5 → NP_788308.3  longitudinals lacking, isoform AA [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788308.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4UZC3, Q867F7, Q867K2, Q867T0, Q867Z4, Q86BC3, Q8MKX6, Q8MZH5
      Conserved Domains (3) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:905 → 925
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain

    13. NM_176133.5 → NP_788313.1  longitudinals lacking, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788313.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4UZC3, Q867F7, Q867K2, Q867T0, Q867Z4, Q86BC3, Q8MKX6, Q8MZH5
      Related
      FBpp0088384
      Conserved Domains (3) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:905 → 925
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain

    14. NM_176134.4 → NP_788314.1  longitudinals lacking, isoform T [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788314.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q867Z4
      Related
      FBpp0088393
      Conserved Domains (3) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00019
      Location:480 → 500
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain

    15. NM_176135.4 → NP_788315.1  longitudinals lacking, isoform U [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788315.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q867Z4
      Related
      FBpp0088385
      Conserved Domains (3) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00019
      Location:480 → 500
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain

    16. NM_170622.6 → NP_724952.2  longitudinals lacking, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724952.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q867Z4
      Related
      FBpp0088382
      Conserved Domains (5) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:507 → 529
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:536 → 555
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain
      pfam13465
      Location:521 → 547
      zf-H2C2_2; Zinc-finger double domain

    17. NM_176136.5 → NP_788316.2  longitudinals lacking, isoform K [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788316.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q867Z4
      Related
      FBpp0088387
      Conserved Domains (4) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00019
      Location:465 → 488
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:495 → 517
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain

    18. NM_206085.4 → NP_995807.1  longitudinals lacking, isoform V [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995807.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42284, Q867M9, Q867R1, Q868A5
      Conserved Domains (2) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain

    19. NM_170620.4 → NP_724950.1  longitudinals lacking, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724950.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7KQZ4
      Related
      FBpp0088383
      Conserved Domains (3) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:481 → 501
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain

    20. NM_170621.4 → NP_724951.1  longitudinals lacking, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724951.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7KQZ4
      Related
      FBpp0088376
      Conserved Domains (3) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:481 → 501
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain

    21. NM_001032229.3 → NP_001027400.1  longitudinals lacking, isoform Z [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001027400.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V5M6
      Conserved Domains (3) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain
      pfam13909
      Location:634 → 658
      zf-H2C2_5; C2H2-type zinc-finger domain

    22. NM_170623.6 → NP_724953.2  longitudinals lacking, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724953.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7KQZ4
      Related
      FBpp0088378
      Conserved Domains (4) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:528 → 545
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain
      pfam05605
      Location:524 → 578
      zf-Di19; Drought induced 19 protein (Di19), zinc-binding

    23. NM_176138.5 → NP_788318.1  longitudinals lacking, isoform L [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788318.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7KQZ4
      Related
      FBpp0088386
      Conserved Domains (4) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00019
      Location:551 → 571
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:578 → 602
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain

    24. NM_176139.3 → NP_788319.1  longitudinals lacking, isoform Q [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788319.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3DMG1
      Related
      FBpp0088390
      Conserved Domains (4) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:546 → 564
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain
      pfam13465
      Location:559 → 584
      zf-H2C2_2; Zinc-finger double domain

    25. NM_176140.4 → NP_788320.1  longitudinals lacking, isoform M [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788320.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42284
      Related
      FBpp0088396
      Conserved Domains (2) summary
      smart00225
      Location:33 → 117
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 117
      BTB; BTB/POZ domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P42283.2 P42283
    P42284.2 P42284
    Q7JPL9 Q7JPL9
    Q7KQZ4.1 Q7KQZ4
    Q867Z4.1 Q867Z4
    Q8IGF5 Q8IGF5
    Q95S45 Q95S45
    Q95TA6 Q95TA6
    Q9V5M3.3 Q9V5M3
    Q9V5M6.4 Q9V5M6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous