Miga2 mitoguardin 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Miga2provided by RGD
Official Full Name: mitoguardin 2provided by RGD
Primary source: RGD:1310887
See related: Ensembl:ENSRNOG00000017513 AllianceGenome:RGD:1310887
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Fam73b; RGD1310887
Summary: Predicted to enable protein heterodimerization activity and protein homodimerization activity. Predicted to be involved in mitochondrial fusion. Predicted to act upstream of or within bone development. Predicted to be integral component of plasma membrane. Orthologous to human MIGA2 (mitoguardin 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 165.3), Adrenal (RPKM 138.7) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 3p12

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (34034018..34056703)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (13636235..13658895)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (8928484..8951189)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables protein heterodimerization activity	ISO Inferred from Sequence Orthology more info
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within bone development	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial fusion	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial fusion	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in mitochondrial outer membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: mitoguardin 2

Names: family with sequence similarity 73, member B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.