CAH1 Carbonic anhydrase 1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CAH1provided by FlyBase
Official Full Name: Carbonic anhydrase 1provided by FlyBase
Primary source: FLYBASE:FBgn0027844
Locus tag: Dmel_CG7820
See related: AllianceGenome:FB:FBgn0027844
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BG:DS00941.1; CAH; CG7820; Dmel\CG7820; Gh7
Summary: Enables carbonate dehydratase activity. Involved in one-carbon metabolic process. Predicted to be active in cytoplasm. Is expressed in adult fat body; adult head; and embryonic/larval midgut. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 3 and osteopetrosis. Orthologous to several human genes including CA2 (carbonic anhydrase 2); CA5A (carbonic anhydrase 5A); and CA5B (carbonic anhydrase 5B). [provided by Alliance of Genome Resources, Apr 2022]
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (13803626..13809994)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (13803626..13809994)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables carbonate dehydratase activity	IBA Inferred from Biological aspect of Ancestor more info
enables carbonate dehydratase activity	IDA Inferred from Direct Assay more info	PubMed
enables carbonate dehydratase activity	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in one-carbon metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in one-carbon metabolic process	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISM Inferred from Sequence Model more info	PubMed

NP_523561.1

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The following sections contain reference sequences that belong to a specific genome build. Explain