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    Dnajc4 DnaJ heat shock protein family (Hsp40) member C4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361717, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Dnajc4provided by RGD
    Official Full Name
    DnaJ heat shock protein family (Hsp40) member C4provided by RGD
    Primary source
    RGD:1308693
    See related
    Ensembl:ENSRNOG00000043060 AllianceGenome:RGD:1308693
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be integral component of membrane. Orthologous to human DNAJC4 (DnaJ heat shock protein family (Hsp40) member C4). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Muscle (RPKM 88.4), Testes (RPKM 84.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    1q43
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (213607397..213611614, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (204178189..204182412, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (222242889..222247115, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene FKBP prolyl isomerase 2 like 1 Neighboring gene FKBP prolyl isomerase 2 Neighboring gene vascular endothelial growth factor B Neighboring gene nudix hydrolase 22 Neighboring gene tRNA phosphotransferase 1 Neighboring gene FERM domain containing kindlin 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    dnaJ homolog subfamily C member 4
    Names
    DnaJ (Hsp40) homolog, subfamily C, member 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013196.1 → NP_001013214.1  dnaJ homolog subfamily C member 4

      See identical proteins and their annotated locations for NP_001013214.1

      Status: PROVISIONAL

      Source sequence(s)
      BC088201
      UniProtKB/TrEMBL
      A0A0G2JTP0, Q5M867
      Related
      ENSRNOP00000028731.4, ENSRNOT00000028731.6
      Conserved Domains (1) summary
      pfam00226
      Location:31 → 93
      DnaJ; DnaJ domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      213607397..213611614 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006230859.5 → XP_006230921.1  dnaJ homolog subfamily C member 4 isoform X2

      UniProtKB/TrEMBL
      A0A0G2JTP0
      Conserved Domains (2) summary
      COG0484
      Location:51 → 115
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      pfam00226
      Location:53 → 115
      DnaJ; DnaJ domain

    2. XM_008760159.4 → XP_008758381.1  dnaJ homolog subfamily C member 4 isoform X1

      See identical proteins and their annotated locations for XP_008758381.1

      UniProtKB/TrEMBL
      A0A0G2JTP0, A0A8I6A600, A6HZM3
      Conserved Domains (1) summary
      pfam00226
      Location:53 → 115
      DnaJ; DnaJ domain

    3. XM_006230860.5 → XP_006230922.1  dnaJ homolog subfamily C member 4 isoform X3

      See identical proteins and their annotated locations for XP_006230922.1

      UniProtKB/TrEMBL
      A0A0G2JTP0, A6HZM4
      Related
      ENSRNOP00000068786.2
      Conserved Domains (2) summary
      COG0484
      Location:35 → 99
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      pfam00226
      Location:37 → 99
      DnaJ; DnaJ domain

    4. XM_039084055.2 → XP_038939983.1  dnaJ homolog subfamily C member 4 isoform X4

      UniProtKB/TrEMBL
      A0A0G2JTP0, Q5M867
      Conserved Domains (1) summary
      pfam00226
      Location:31 → 93
      DnaJ; DnaJ domain

    5. XM_039084060.1 → XP_038939988.1  dnaJ homolog subfamily C member 4 isoform X5

      UniProtKB/TrEMBL
      A0A0G2JTP0
      Conserved Domains (1) summary
      pfam00226
      Location:20 → 82
      DnaJ; DnaJ domain
    Nucleotide Protein Strain
    Heading Accession and Version

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