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    Mpcp1 Mitochondrial phosphate carrier protein 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37297, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Mpcp1provided by FlyBase
    Official Full Name
    Mitochondrial phosphate carrier protein 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0034497
    Locus tag
    Dmel_CG9090
    See related
    AllianceGenome:FB:FBgn0034497
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9090; Dmel\CG9090; DmPiC1; Mpc1
    Summary
    Predicted to enable inorganic phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in mitochondrion. Predicted to be integral component of mitochondrial inner membrane. Is expressed in adult head; adult heart; and organism. Orthologous to human SLC25A3 (solute carrier family 25 member 3). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See Mpcp1 in Genome Data Viewer
    Location:
    56F15-56F16; 2-90 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20279066..20281127, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16166571..16168632, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tissue-specific expression and silencing phenotypes of mitochondrial phosphate carrier paralogues in several insect species. Sugahara R, et al. Insect Mol Biol, 2017 Jun. PMID 28224717
    2. The contributions of sex, genotype and age to transcriptional variance in Drosophila melanogaster. Jin W, et al. Nat Genet, 2001 Dec. PMID 11726925
    3. Aralar Sequesters GABA into Hyperactive Mitochondria, Causing Social Behavior Deficits. Kanellopoulos AK, et al. Cell, 2020 Mar 19. PMID 32200800
    4. Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain. Mukherjee C, et al. Cell Metab, 2020 Aug 4. PMID 32531201, Free PMC Article
    5. Proteomic characterization of a temperature-sensitive conditional lethal in Drosophila melanogaster. Pedersen KS, et al. Heredity (Edinb), 2010 Feb. PMID 19812620

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables phosphate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphate transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial phosphate ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phosphate ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphate ion transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial phosphate carrier protein 1
    Names
    CG9090-PA
    CG9090-PB
    CG9090-PC
    Mpcp1-PA
    Mpcp1-PB
    Mpcp1-PC
    mitochondrial phosphate carrier 1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20279066..20281127 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137624.2 → NP_611468.1  mitochondrial phosphate carrier protein 1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611468.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JUS9
      Related
      FBpp0085615
      Conserved Domains (1) summary
      pfam00153
      Location:71 → 160
      Mito_carr; Mitochondrial carrier protein

    2. NM_001299699.1 → NP_001286628.1  mitochondrial phosphate carrier protein 1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286628.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JUS9
      Conserved Domains (1) summary
      pfam00153
      Location:71 → 160
      Mito_carr; Mitochondrial carrier protein

    3. NM_001299700.1 → NP_001286629.1  mitochondrial phosphate carrier protein 1, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286629.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JUS9
      Conserved Domains (1) summary
      pfam00153
      Location:71 → 160
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JUS9 Q7JUS9

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