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    CG1909 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43800, updated on 4-Apr-2024

    Summary

    Official Symbol
    CG1909provided by FlyBase
    Primary source
    FLYBASE:FBgn0039911
    Locus tag
    Dmel_CG1909
    See related
    AllianceGenome:FB:FBgn0039911
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG1909
    Summary
    Predicted to enable acetylcholine receptor binding activity and zinc ion binding activity. Predicted to be involved in cholinergic synaptic transmission. Is expressed in adult head. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 11 and fetal akinesia deformation sequence syndrome 2. Orthologous to human RAPSN (receptor associated protein of the synapse). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    Location:
    102C6-102C6; 4-0 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 4 NC_004353.4 (583108..589348)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 4 NC_004353.3 (603734..609974)

    Chromosome 4 - NC_004353.4Genomic Context describing neighboring genes Neighboring gene NADH dehydrogenase (ubiquinone) 49 kDa subunit Neighboring gene ephrin Neighboring gene long non-coding RNA:CR45199 Neighboring gene onecut

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    mobile_element

    • Loc: 586587-586659 mobile_element_type = transposon:INE-1{}6119

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables acetylcholine receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables acetylcholine receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables acetylcholine receptor binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables protein-membrane adaptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of neuromuscular synaptic transmission IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in synaptic transmission, cholinergic IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in synaptic transmission, cholinergic ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in neuromuscular junction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG1909-PA
    CG1909-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004353.4 Reference assembly

      Range
      583108..589348
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143671.3NP_651928.1  uncharacterized protein Dmel_CG1909, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651928.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K4Y8
      Related
      FBpp0088148
      Conserved Domains (3) summary
      sd00006
      Location:94122
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:249322
      TPR_12; Tetratricopeptide repeat
      cl24038
      Location:89168
      SNAP; Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family
    2. NM_166773.2NP_726586.1  uncharacterized protein Dmel_CG1909, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726586.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K4Y8
      Related
      FBpp0088149
      Conserved Domains (3) summary
      sd00006
      Location:94122
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:249322
      TPR_12; Tetratricopeptide repeat
      cl24038
      Location:89168
      SNAP; Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family