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    ctnnbip1 catenin, beta interacting protein 1 [ Danio rerio (zebrafish) ]

    Gene ID: 58117, updated on 27-Mar-2024

    Summary

    Official Symbol
    ctnnbip1provided by ZNC
    Official Full Name
    catenin, beta interacting protein 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-000906-3
    See related
    Ensembl:ENSDARG00000038954 AllianceGenome:ZFIN:ZDB-GENE-000906-3
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    icat; fa95e12; wu:fa95e12
    Summary
    Predicted to enable beta-catenin binding activity. Predicted to be involved in negative regulation of Wnt signaling pathway. Predicted to be part of beta-catenin destruction complex. Predicted to be active in cytosol and nucleus. Is expressed in central nervous system and optic tectum. Orthologous to human CTNNBIP1 (catenin beta interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    Location:
    chromosome: 23
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (29711569..29751730, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (29785028..29825189, complement)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene leucine zipper and CTNNBIP1 domain containing Neighboring gene calsyntenin 1 Neighboring gene phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta Neighboring gene forkhead box L2-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables beta-catenin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables beta-catenin binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within negative regulation of Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of beta-catenin destruction complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    beta-catenin-interacting protein 1
    Names
    beta-catenin-interacting protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131594.1NP_571669.1  beta-catenin-interacting protein 1

      See identical proteins and their annotated locations for NP_571669.1

      Status: PROVISIONAL

      Source sequence(s)
      AB046866
      UniProtKB/TrEMBL
      Q789J2, Q9I903
      Related
      ENSDARP00000056864.4, ENSDART00000056865.6
      Conserved Domains (1) summary
      pfam06384
      Location:179
      ICAT; Beta-catenin-interacting protein ICAT

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      29711569..29751730 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)